Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 13/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 12/20 | 0.49 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.49 |
| ▸ | SIRT5 | Q9NXA8 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16579973 | 0.92 | SIRT2 (0.52) | SIRT2SIRT1SIRT3SIRT5MEN1 | |
| SCHEMBL16579975 | 0.90 | SIRT2 (0.44) | SIRT2SIRT1SIRT3SIRT5MEN1 | |
| SCHEMBL16580030 | 0.90 | SIRT2 (0.44) | SIRT2SIRT1SIRT3SIRT5MEN1 | |
| SCHEMBL19783967 | 0.88 | CA2 (0.51) | SIRT2SIRT1SIRT3SIRT5MEN1 | |
| SCHEMBL20282050 | 0.88 | CA2 (0.51) | SIRT2SIRT1SIRT3SIRT5MEN1 | |
| SCHEMBL17484948 | 0.87 | SIRT2 (0.48) | SIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL19784482 | 0.86 | SIRT2 (0.49) | SIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL22387920 | 0.86 | SIRT2 (0.55) | SIRT2SIRT1SIRT3SIRT5MEN1 | |
| SCHEMBL13814439 | 0.86 | SIRT2 (0.55) | SIRT2SIRT1SIRT3SIRT5MEN1 | |
| SCHEMBL22387792 | 0.85 | SIRT2 (0.54) | SIRT2SIRT1SIRT3SIRT5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4213884-A1 | MOLECULES WITH SOLUBILITY TAG AND RELATED METHODS | Merck Patent GmbH (DE) | 2023-07-26 | — | — | EP | disclosed |
| WO-2022058548-A1 | MOLECULES WITH SOLUBILITY TAG AND RELATED METHODS | MERCK PATENT GMBH (DE) | 2022-03-24 | — | — | WO | disclosed |
| WO-2022058548-A1 | MOLECULES WITH SOLUBILITY TAG AND RELATED METHODS | MERCK PATENT GMBH (DE) | 2022-03-24 | — | — | WO | disclosed |