SCHEMBL24277902

SCHEMBL24277902

C=C/C(=C\C=C/C)c1ccc(-n2c3ccccc3c3c4c5ccccc5n(-c5ccc6c(c5)c5ccccc5n6-c5ccccc5)c4ccc32)cc1

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 3/20 0.38
▸ ATM Q13315 1/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.38
▸ PTGER4 P35408 4/20 0.32
▸ PTPN1 P18031 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.31
▸ HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23233615 0.89 KDM4E (0.34) KDM4EATML3MBTL1
SCHEMBL23282842 0.87 KDM4E (0.36) KDM4EATML3MBTL1PTGER4
SCHEMBL23282793 0.86 TSPO (0.37) KDM4EATML3MBTL1PTGER4PTPN1
SCHEMBL26005669 0.85 PTGER4 (0.35) PTGER4
SCHEMBL22133343 0.84 KDM4E (0.45) KDM4EATML3MBTL1PTPN1ALDH1A1
SCHEMBL25964611 0.81 PTGER4 (0.34) PTGER4
SCHEMBL24159880 0.81 CYP2C9 (0.33) —
SCHEMBL25672312 0.81 KDM4E (0.35) KDM4EATML3MBTL1PTGER4PTPN1
SCHEMBL23676832 0.79 PTGER4 (0.33) KDM4EPTGER4ALDH1A1HPGD
SCHEMBL23280787 0.78 PTGER4 (0.34) KDM4EATML3MBTL1PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230320210-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-05 — — US disclosed
US-11700766-B2 Host materials for electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-11 — — US disclosed
US-20220093876-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-03-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11700766-B2 Host materials for electroluminescent devices OR10J3, OCIAD2, MCM4 KDM4E 2981/4885ATM 4507/4885L3MBTL1 2241/4885
US-20220093876-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES OR10J3, OCIAD2, MCM4 KDM4E 2981/4885ATM 4507/4885L3MBTL1 2241/4885
US-20230320210-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES OR10J3, OCIAD2, MCM4 KDM4E 2981/4885ATM 4507/4885L3MBTL1 2241/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback