Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Tetrabuthylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.67 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.53 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.53 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.53 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.51 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.51 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.51 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.49 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.49 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.49 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.47 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.44 |
| ▸ | ARG1 | P05089 | 3/20 | 0.43 |
| ▸ | ARG2 | P78540 | 3/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 3/20 | 0.43 |
| ▸ | NOS3 | P29474 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrabuthylammonium SCHEMBL242784 | 1.00 | GSR (0.67) | GSRGNAI3GNAO1GNAI1GRIK1 | |
| Tetrahexylammonium SCHEMBL28700729 | 0.95 | GSR (0.65) | GSRGNAI3GNAO1GNAI1GRIK1 | |
| Tetrahexylammonium SCHEMBL28700732 | 0.95 | GSR (0.65) | GSRGNAI3GNAO1GNAI1GRIK1 | |
| Lysine SCHEMBL26634433 | 0.91 | GSR (0.80) | GSRGNAI3GNAO1GNAI1GRIK1 | |
| Lysine SCHEMBL28088035 | 0.91 | GSR (0.80) | GSRGNAI3GNAO1GNAI1GRIK1 | |
| Octadecylamine SCHEMBL9458206 | 0.90 | GSR (0.77) | GSRGNAI3GNAO1GNAI1GRIK1 | |
| Lysine SCHEMBL9404153 | 0.90 | GSR (0.77) | GSRGNAI3GNAO1GNAI1GRIK1 | |
| Dodecylamine SCHEMBL9441770 | 0.90 | GSR (0.77) | GSRGNAI3GNAO1GNAI1GRIK1 | |
| Dodecylamine SCHEMBL9441764 | 0.90 | GSR (0.77) | GSRGNAI3GNAO1GNAI1GRIK1 | |
| Octadecylamine SCHEMBL9458208 | 0.90 | GSR (0.77) | GSRGNAI3GNAO1GNAI1GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112592427-B | Macroporous adsorption resin and preparation method thereof | 蚌埠市天星树脂有限责任公司 | 2021-07-20 | — | — | CN | claimed |
| CN-112592427-A | Macroporous adsorption resin and preparation method thereof | 蚌埠市天星树脂有限责任公司 | 2021-04-02 | — | — | CN | claimed |
| CN-117654442-A | Modified porous adsorption material for removing formaldehyde and preparation method thereof | 佛山市顺德区阿波罗环保器材有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-112592427-B | Macroporous adsorption resin and preparation method thereof | 蚌埠市天星树脂有限责任公司 | 2021-07-20 | — | — | CN | disclosed |
| CN-112592427-A | Macroporous adsorption resin and preparation method thereof | 蚌埠市天星树脂有限责任公司 | 2021-04-02 | — | — | CN | disclosed |
| EP-2064251-B1 | BIOMIMETIC COMPOUNDS AND SYNTHETIC METHODS THEREFOR | KENSEY NASH CORP (US) | 2017-10-25 | — | — | EP | disclosed |
| EP-2334305-B1 | BIOADHESIVE CONSTRUCTS | KENSEY NASH CORP (US) | 2015-04-22 | — | — | EP | disclosed |
| US-8575276-B2 | Biomimetic compounds and synthetic methods therefor | KNC NER ACQUISITION SUB, INC. (US) | 2013-11-05 | — | — | US | disclosed |
| US-8383092-B2 | Bioadhesive constructs | KNC NER ACQUISITION SUB, INC. (US) | 2013-02-26 | — | — | US | disclosed |
| US-20120078296-A1 | BIOMIMETIC COMPOUNDS AND SYNTHETIC METHODS THEREFOR | KNC NER ACQUISITION SUB, INC. (US) | 2012-03-29 | — | — | US | disclosed |
| US-20120003888-A1 | BIOADHESIVE CONSTRUCTS WITH POLYMER BLENDS | KNC NER ACQUISITION SUB, INC. (US) | 2012-01-05 | — | — | US | disclosed |
| US-20100197868-A1 | BIOMIMETIC COMPOUNDS AND SYNTHETIC METHODS THEREFOR | NERITES CORPORATION (US) | 2010-08-05 | — | — | US | disclosed |
| US-20100137903-A1 | BIOADHESIVE CONSTRUCTS | NERITES CORPORATION (US) | 2010-06-03 | — | — | US | disclosed |
| US-20100137902-A1 | BIOADHESIVE CONSTRUCTS | NERITES CORPORATION (US) | 2010-06-03 | — | — | US | disclosed |
| WO-2010037044-A1 | BIOADHESIVE CONSTRUCTS | NERITES CORPORATION (US) | 2010-04-01 | — | — | WO | disclosed |
| US-7622533-B2 | Biomimetic compounds and synthetic methods therefor | NERITES CORPORATION (US) | 2009-11-24 | — | — | US | disclosed |
| EP-2064251-A1 | BIOMIMETIC COMPOUNDS AND SYNTHETIC METHODS THEREFOR | Nerites Corporation (US) | 2009-06-03 | — | — | EP | disclosed |
| US-20090076241-A1 | BIOMIMETIC COMPOUNDS AND SYNTHETIC METHODS THEREFOR | NERITES CORPORATION | 2009-03-19 | — | — | US | disclosed |
| US-20080171836-A1 | BIOMIMETIC COMPOUNDS AND SYNTHETIC METHODS THEREFOR | KENSEY NASH CORPORATION | 2008-07-17 | — | — | US | disclosed |
| WO-2008019352-A1 | BIOMIMETIC COMPOUNDS AND SYNTHETIC METHODS THEREFOR | NERITES CORPORATION (US) | 2008-02-14 | — | — | WO | disclosed |