Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.78 |
| ▸ | MAOB | P27338 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.55 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.55 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.55 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.55 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.55 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16224303 | 0.87 | RRM1 (0.59) | POLBMAOBKDM4ELMNAHTT | |
| SCHEMBL17560960 | 0.87 | RRM1 (0.59) | POLBMAOBKDM4ELMNAHTT | |
| SCHEMBL5180084 | 0.84 | NPC1 (0.59) | POLBKDM4ELMNAGRIN2DGRIN3B | |
| SCHEMBL5180081 | 0.84 | NPC1 (0.59) | POLBKDM4ELMNAGRIN2DGRIN3B | |
| SCHEMBL7748676 | 0.84 | GRIN2D (0.55) | POLBMAOBKDM4ELMNAGRIN2D | |
| SCHEMBL7748673 | 0.84 | GRIN2D (0.55) | POLBMAOBKDM4ELMNAGRIN2D | |
| Hydrochloric Acid SCHEMBL5703045 | 0.83 | GRIN2D (0.56) | POLBMAOBKDM4ELMNAGRIN2D | |
| Hydrochloric Acid SCHEMBL5703049 | 0.83 | GRIN2D (0.56) | POLBMAOBKDM4ELMNAGRIN2D | |
| SCHEMBL5181515 | 0.82 | POLB (0.81) | POLBMAOBKDM4ELMNAHTT | |
| SCHEMBL31222602 | 0.82 | POLB (0.81) | POLBMAOBKDM4ELMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3960729-A1 | COMPOUNDS AND METHODS OF TREATING INFECTIONS | Neoculi Pty Ltd (AU) | 2022-03-02 | — | — | EP | disclosed |