Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 11/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24279192 | 0.93 | PDK1 (0.40) | CHRNA7PDK1TSHRCYP2C19HIF1A | |
| SCHEMBL24279194 | 0.88 | CHRNA7 (0.39) | CHRNA7ADORA2AADORA1 | |
| SCHEMBL21686477 | 0.86 | CHRNA7 (0.35) | CHRNA7PDK1 | |
| SCHEMBL24282175 | 0.86 | CHRNA7 (0.40) | CHRNA7ADORA2AADORA1ESR1ESR2 | |
| SCHEMBL24279208 | 0.81 | CHRNA7 (0.41) | CHRNA7ADORA2AADORA1HSP90AA1 | |
| SCHEMBL21686442 | 0.81 | PDK1 (0.42) | CHRNA7PDK1TSHRCYP2C19HIF1A | |
| SCHEMBL24279191 | 0.80 | MAPT (0.34) | CHRNA7PDK1ESR1ESR2 | |
| SCHEMBL21686440 | 0.78 | CHRNA7 (0.36) | CHRNA7ADORA2AADORA1HSP90AA1 | |
| SCHEMBL24282176 | 0.78 | MEN1 (0.42) | CHRNA7ESR1ESR2 | |
| SCHEMBL24358415 | 0.77 | MAPT (0.51) | CHRNA7ADORA2AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3362518-B1 | SENSOR DYES FOR REAL-TIME SENSING OF METAL IONS IN AQUEOUS ENVIRONMENTS | THE UWM RES FOUNDATION INC (US) | 2022-04-27 | — | — | EP | disclosed |
| US-11275071-B2 | Sensor dyes for real-time sensing of metal ions in aqueous environments | UWM RESEARCH FOUNDATION, INC. (US) | 2022-03-15 | — | — | US | disclosed |