Amiquinsin

Amiquinsin

SCHEMBL242841

COc1cc2nccc(N)c2cc1OC

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EHMT2 Q96KQ7 1/20 0.63
EHMT1 Q9H9B1 1/20 0.63
PDGFRB P09619 1/20 0.55
PDGFRA P16234 1/20 0.55
EGFR P00533 2/20 0.53
SRC P12931 2/20 0.51
BMPR1B O00238 1/20 0.51
GAK O14976 1/20 0.51
EPHB6 O15197 1/20 0.51
RIPK2 O43353 1/20 0.51
ABL1 P00519 1/20 0.51
LCK P06239 1/20 0.51
EPHA1 P21709 1/20 0.51
EPHA8 P29322 1/20 0.51
ACVR1 Q04771 1/20 0.51
MAP2K5 Q13163 1/20 0.51
COQ8A Q8NI60 1/20 0.51
NLK Q9UBE8 1/20 0.51
KDR P35968 1/20 0.51
NCF1 P14598 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Amiquinsin SCHEMBL30616015 0.98 EHMT2 (0.61) EHMT2EHMT1PDGFRBPDGFRAEGFR
Amiquinsin SCHEMBL122139 0.96 EHMT2 (0.60) EHMT2EHMT1PDGFRBPDGFRAEGFR
Amiquinsin SCHEMBL27533387 0.88 EHMT2 (0.53) EHMT2EHMT1PDGFRBPDGFRAEGFR
SCHEMBL4400367 0.84 PDGFRB (0.72) PDGFRBPDGFRAEGFRSRCFGFR2
Amiquinsin SCHEMBL31187496 0.82 EHMT2 (0.47) EHMT2EHMT1PDGFRBPDGFRAEGFR
SCHEMBL29736268 0.82 EHMT2 (0.60) EHMT2EHMT1EGFRGAKKDR
SCHEMBL1496287 0.79 PDGFRB (0.57) PDGFRBPDGFRAEGFRSRCBMPR1B
SCHEMBL4480466 0.79 PDGFRB (0.61) PDGFRBPDGFRAEGFRSRCKDR
SCHEMBL29079702 0.79 PDGFRB (0.60) PDGFRBPDGFRAEGFRSRCFGFR2
SCHEMBL30574469 0.79 PDGFRB (0.60) PDGFRBPDGFRAEGFRSRCFGFR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-4868182-A HYPOTENSIVE AND CARDIOTONIC, SYNERGISTIC MERRELL DOW PHARMACEUTICALS INC. (US) 1989-09-19 US claimed
WO-2024194756-A1 MODULATING THE INNATE IMMUNITY OF RNA PFIZER INC. (US) 2024-09-26 WO disclosed
CN-114957136-A Anti-tumor compound used as VEGFR inhibitor and application thereof 南京科默生物医药有限公司 2022-08-30 CN disclosed
US-20220047505-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2022-02-17 US disclosed
US-11191719-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2021-12-07 US disclosed
US-10463611-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2019-11-05 US disclosed
WO-2019177971-A1 ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE 1 (ENPP-1) INHIBITORS AND USES THEREOF MAVUPHARMA, INC. (US) 2019-09-19 WO disclosed
US-4686228-A Quinoline therapeutic agents PFIZER INC. (US) 1987-08-11 US disclosed
EP-0100200-B1 2-SUBSTITUTED 4-AMINO-6,7-DIMETHOXYQUINOLINES Pfizer Limited (GB) 1987-05-06 EP disclosed
EP-0100200-B1 2-SUBSTITUTED 4-AMINO-6,7-DIMETHOXYQUINOLINES Pfizer Limited (GB) 1987-05-06 EP disclosed
US-4656174-A HYPOTENSIVE AGENTS PFIZER INC. (US) 1987-04-07 US disclosed
EP-0100200-A1 2-Substituted 4-amino-6,7-dimethoxyquinolines Pfizer Limited (GB) 1984-02-08 EP disclosed
EP-0100200-A1 2-Substituted 4-amino-6,7-dimethoxyquinolines Pfizer Limited (GB) 1984-02-08 EP disclosed
EP-0100200-A1 2-Substituted 4-amino-6,7-dimethoxyquinolines Pfizer Limited (GB) 1984-02-08 EP disclosed