Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12113898 | 0.85 | PLK1 (0.79) | PLK1TP53TSHR | |
| SCHEMBL14969349 | 0.85 | PLK1 (0.79) | PLK1TP53TSHR | |
| SCHEMBL12112441 | 0.85 | PLK1 (0.79) | PLK1TP53TSHR | |
| SCHEMBL19723266 | 0.85 | MAPT (0.65) | MAPTSMN1; SMN2MEN1KMT2AMMP1 | |
| SCHEMBL14969336 | 0.84 | PLK1 (0.81) | PLK1SMN1; SMN2MMP1TP53TSHR | |
| SCHEMBL12839873 | 0.84 | PLK1 (0.87) | PLK1SMN1; SMN2MEN1KMT2AMMP1 | |
| SCHEMBL11758823 | 0.83 | NPC1 (0.72) | MAPTSMN1; SMN2MEN1KMT2AMMP1 | |
| SCHEMBL9490019 | 0.83 | NPC1 (0.72) | MAPTSMN1; SMN2MEN1KMT2AMMP1 | |
| SCHEMBL11758728 | 0.82 | NPC1 (0.77) | MAPTSMN1; SMN2MEN1KMT2AMMP1 | |
| SCHEMBL7749263 | 0.81 | CNR2 (0.65) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022052014-A1 | CLASS OF PLATINUM COMPOUNDS FOR TREATING CANCER, AND METHOD FOR PREPARATION THEREOF | 上海海聚生物科技有限公司 | 2022-03-17 | — | — | WO | disclosed |