Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 15/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 15/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.37 |
| ▸ | VNN1 | O95497 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.35 |
| ▸ | MERTK | Q12866 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27095229 | 0.81 | VNN1 (0.42) | CYP11B1CYP11B2VNN1 | |
| SCHEMBL27095184 | 0.79 | IRAK4 (0.42) | CYP11B1CYP11B2HRH4AXLTYRO3 | |
| SCHEMBL27137336 | 0.79 | IRAK4 (0.42) | CYP11B1CYP11B2HRH4AXLTYRO3 | |
| Formic Acid SCHEMBL30838066 | 0.78 | HRH4 (0.44) | CYP11B1CYP11B2HRH4VNN1AXL | |
| Formic Acid SCHEMBL30838087 | 0.78 | HRH4 (0.41) | CYP11B1CYP11B2HRH4AXLTYRO3 | |
| Formic Acid SCHEMBL30838050 | 0.77 | VNN1 (0.55) | CYP11B1CYP11B2VNN1 | |
| Formic Acid SCHEMBL30838102 | 0.77 | VNN1 (0.55) | CYP11B1CYP11B2VNN1 | |
| SCHEMBL27137884 | 0.77 | CYP11B1 (0.36) | CYP11B1CYP11B2HRH4 | |
| SCHEMBL27095203 | 0.77 | CYP11B1 (0.36) | CYP11B1CYP11B2HRH4 | |
| Hydrochloric Acid SCHEMBL30838036 | 0.77 | IDO1 (0.43) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022053823-A1 | SUBSTITUTED PYRIMIDINE DERIVATIVES AS NICOTINIC ACETYLCHOLINESTERASE RECEPTOR ALPHA 6 MODULATOR | Cerevance, Inc. (US) | 2022-03-17 | — | — | WO | disclosed |