Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 8/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.41 |
| ▸ | USP1 | O94782 | 1/20 | 0.39 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CCNK | O75909 | 1/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.36 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24288237 | 0.88 | PRKCQ (0.48) | PRKCQHRH4SCN9A | |
| SCHEMBL27095173 | 0.84 | PRKCQ (0.50) | PRKCQHRH4CCNE1CDK2 | |
| Hydrochloric Acid SCHEMBL30838083 | 0.84 | PRKCQ (0.49) | PRKCQHRH4 | |
| Hydrochloric Acid SCHEMBL30838056 | 0.84 | PRKCQ (0.49) | PRKCQHRH4CCNE1CDK2 | |
| SCHEMBL24288090 | 0.81 | HRH4 (0.45) | PRKCQHRH4CHRM3CCNT1CDK9 | |
| Hydrochloric Acid SCHEMBL30838015 | 0.80 | HRH4 (0.45) | PRKCQHRH4CHRM3CCNT1CDK9 | |
| Formic Acid SCHEMBL30838073 | 0.80 | PRKCQ (0.41) | PRKCQHRH4 | |
| SCHEMBL24288241 | 0.77 | PRKCQ (0.39) | PRKCQHRH4 | |
| Formic Acid SCHEMBL30838087 | 0.74 | HRH4 (0.41) | HRH4 | |
| Hydrochloric Acid SCHEMBL30838055 | 0.73 | PRKCQ (0.40) | PRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022053823-A1 | SUBSTITUTED PYRIMIDINE DERIVATIVES AS NICOTINIC ACETYLCHOLINESTERASE RECEPTOR ALPHA 6 MODULATOR | Cerevance, Inc. (US) | 2022-03-17 | — | — | WO | disclosed |