Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20901061 | 0.97 | MEN1 (0.37) | KMT2AMEN1LMNAKDM4EBRAF | |
| SCHEMBL24281339 | 0.97 | BRAF (0.38) | KMT2AMEN1LMNAKDM4EBRAF | |
| SCHEMBL20050387 | 0.97 | BRAF (0.38) | KMT2AMEN1LMNAKDM4EBRAF | |
| SCHEMBL20051184 | 0.94 | MEN1 (0.39) | KMT2AMEN1LMNABRAFGRM4 | |
| SCHEMBL20050883 | 0.94 | PDK1 (0.41) | KMT2AMEN1LMNAKDM4EBRAF | |
| SCHEMBL20051641 | 0.93 | KMT2A (0.36) | KMT2AMEN1LMNAKDM4EBRAF | |
| SCHEMBL30739849 | 0.93 | KMT2A (0.36) | KMT2AMEN1LMNAKDM4EBRAF | |
| SCHEMBL20050471 | 0.93 | KMT2A (0.36) | KMT2AMEN1LMNAKDM4EBRAF | |
| SCHEMBL20051201 | 0.93 | KMT2A (0.36) | KMT2AMEN1LMNAKDM4EBRAF | |
| SCHEMBL20051640 | 0.92 | KMT2A (0.35) | KMT2AMEN1LMNAKDM4EBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3964495-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND COMPOSITIONS, AND PROCESSES, RELATED THERETO | Dow AgroSciences LLC (US) | 2022-03-09 | — | — | EP | disclosed |