Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24289311 | 0.84 | KDM4E (0.36) | NPSR1CYP3A4POLBGAA | |
| SCHEMBL24289836 | 0.73 | MAPT (0.47) | NPSR1TDP1CYP3A4POLBGAA | |
| SCHEMBL24290107 | 0.71 | BRD4 (0.43) | BRD4BCHECYP3A4DRD2 | |
| SCHEMBL30875359 | 0.71 | BRD4 (0.43) | BRD4BCHECYP3A4DRD2 | |
| SCHEMBL30875386 | 0.70 | BRD4 (0.45) | BRD4BCHECYP3A4DRD2 | |
| SCHEMBL24289950 | 0.69 | GAA (0.44) | NPSR1TDP1CYP3A4POLBGAA | |
| SCHEMBL1754974 | 0.67 | BCHE (0.54) | BRD4BCHEGAA | |
| SCHEMBL21224591 | 0.67 | TDP1 (0.58) | BRD4NPSR1TDP1CYP3A4DRD2 | |
| SCHEMBL3531115 | 0.66 | CA12 (0.50) | BRD4BCHENPSR1TDP1CYP3A4 | |
| SCHEMBL7873171 | 0.66 | TDP1 (0.69) | NPSR1TDP1CYP3A4DRD2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022073469-A1 | COMPOUNDS AND METHODS OF TREATING CANCERS | CULLGEN (SHANGHAI) , INC. (CN) | 2022-04-14 | — | — | WO | disclosed |