Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | BRD4 | O60885 | 4/20 | 0.47 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13056573 | 0.81 | MEN1 (0.40) | BCHEMEN1NPC1GAARAB9A | |
| SCHEMBL13056570 | 0.76 | NQO2 (0.46) | MEN1NPC1RAB9AKMT2ANQO2 | |
| SCHEMBL28027633 | 0.76 | KCNA5 (0.56) | BCHEMALT1MEN1GAAKMT2A | |
| SCHEMBL521735 | 0.76 | EGLN1 (0.60) | BCHENQO2 | |
| SCHEMBL1754810 | 0.75 | POLB (0.58) | BCHEMALT1NPC1GAARAB9A | |
| SCHEMBL1657927 | 0.74 | ESRRG (0.56) | BCHEMALT1MEN1NPC1GAA | |
| SCHEMBL2849313 | 0.74 | BCHE (0.48) | BCHEBRD4MALT1MEN1GAA | |
| SCHEMBL2632886 | 0.74 | TDP1 (0.45) | BCHEMALT1MEN1GAAKMT2A | |
| SCHEMBL23308032 | 0.73 | SMN1; SMN2 (0.43) | NPC1GAARAB9A | |
| SCHEMBL15286381 | 0.73 | BCHE (0.61) | BCHEBRD4MALT1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11345719-B2 | Protein proximity assay in formalin fixed paraffin embedded tissue using caged haptens | Vetana Medical Systems, Inc. (US) | 2022-05-31 | — | — | US | disclosed |
| US-20210309680-A1 | PROTEIN PROXIMITY ASSAY IN FORMALIN FIXED PAFFAFIN EMBEDDED TISSUE USING CAGED HAPTENS | VENTANA MED SYST INC (US) | 2021-10-07 | — | — | US | disclosed |
| US-11092594-B2 | Haptens, hapten conjugates, compositions thereof and method for their preparation and use | VENTANA MEDICAL SYSTEMS, INC. (US) | 2021-08-17 | — | — | US | disclosed |
| US-20210221833-A1 | PROTEIN PROXIMITY ASSAY IN FORMALIN FIXED PARAFFIN EMBEDDED TISSUE USING CAGED HAPTENS | VENTANA MED SYST INC (US) | 2021-07-22 | — | — | US | disclosed |
| US-11053266-B2 | Protein proximity assay in formalin fixed paffafin embedded tissue using caged haptens | VENTANA MEDICAL SYSTEMS, INC. (US) | 2021-07-06 | — | — | US | disclosed |
| EP-3564674-A1 | HAPTENS, HAPTEN CONJUGATES, COMPOSITIONS THEREOF AND METHOD FOR THEIR PREPARATION AND USE | Ventana Medical Systems, Inc. (US) | 2019-11-06 | — | — | EP | disclosed |
| EP-3276349-B1 | HAPTENS, HAPTEN CONJUGATES, COMPOSITIONS THEREOF AND METHOD FOR THEIR PREPARATION AND USE | VENTANA MED SYST INC (US) | 2019-08-07 | — | — | EP | disclosed |
| US-20190233447-A1 | PROTEIN PROXIMITY ASSAY IN FORMALIN FIXED PARAFFIN EMBEDDED TISSUE USING CAGED HAPTENS | VENTANA MEDICAL SYSTEMS, INC. | 2019-08-01 | — | — | US | disclosed |
| US-20180186821-A1 | PROTEIN PROXIMITY ASSAY IN FORMALIN FIXED PAFFAFIN EMBEDDED TISSUE USING CAGED HAPTENS | VENTANA MEDICAL SYSTEMS, INC. | 2018-07-05 | — | — | US | disclosed |
| US-20180120306-A1 | HAPTENS, HAPTEN CONJUGATES, COMPOSITIONS THEREOF AND METHOD FOR THEIR PREPARATION AND USE | VENTANA MED SYST INC (US) | 2018-05-03 | — | — | US | disclosed |
| US-8846320-B2 | Haptens, hapten conjugates, compositions thereof and method for their preparation and use | VENTANA MEDICAL SYSTEMS, INC. (US) | 2014-09-30 | — | — | US | disclosed |
| EP-2444806-B1 | Haptens, hapten conjugates, compositions thereof and method for their preparation and use | VENTANA MED SYST INC (US) | 2014-05-28 | — | — | EP | disclosed |
| EP-2444806-A2 | Haptens, hapten conjugates, compositions thereof and method for their preparation and use | Ventana Medical Systems, Inc. (US) | 2012-04-25 | — | — | EP | disclosed |
| EP-2444807-A2 | HAPTENS, HAPTEN CONJUGATES, COMPOSITIONS THEREOF AND METHOD FOR THEIR PREPARATION AND USE | Ventana Medical Systems, Inc. (US) | 2012-04-25 | — | — | EP | disclosed |
| EP-2442107-A2 | Haptens, hapten conjugates, compositions thereof and method for their preparation and use | Ventana Medical Systems, Inc. (US) | 2012-04-18 | — | — | EP | disclosed |
| US-20100297725-A1 | Haptens, hapten conjugates, compositions thereof and method for their preparation and use | VENTANA MEDICAL SYSTEMS, INC. | 2010-11-25 | — | — | US | disclosed |
| US-20100184087-A1 | Haptens, hapten conjugates, compositions thereof and method for their preparation and use | VENTANA MEDICAL SYSTEMS, INC. | 2010-07-22 | — | — | US | disclosed |
| US-7695929-B2 | Derivatives containing oxazole, pyrazole, thiazole, nitroaryl compound, benzofurazan, triterpene, urea, thiourea, rotenoid, coumarin or cyclolignan such as 4-(2-hydroxyphenyl)-1H-benzo[b][1,4]diazepine-2(3H)-one; multiplexed diagnostic assay for multiple targets in sample; antibodies; kits | VENTANA MEDICAL SYSTEMS, INC. (US) | 2010-04-13 | — | — | US | disclosed |
| US-20080268462-A1 | Derivatives containing oxazole, pyrazole, thiazole, nitroaryl compound, benzofurazan, triterpene, urea, thiourea, rotenoid, coumarin or cyclolignan such as 4-(2-hydroxyphenyl)-1H-benzo[b][1,4]diazepine-2(3H)-one; multiplexed diagnostic assay for multiple targets in sample; antibodies; kits | VENTANA MEDICAL SYSTEMS, INC. | 2008-10-30 | — | — | US | disclosed |
| US-20080268462-A1 | Derivatives containing oxazole, pyrazole, thiazole, nitroaryl compound, benzofurazan, triterpene, urea, thiourea, rotenoid, coumarin or cyclolignan such as 4-(2-hydroxyphenyl)-1H-benzo[b][1,4]diazepine-2(3H)-one; multiplexed diagnostic assay for multiple targets in sample; antibodies; kits | VENTANA MEDICAL SYSTEMS, INC. | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210309680-A1 | PROTEIN PROXIMITY ASSAY IN FORMALIN FIXED PAFFAFIN EMBEDDED TISSUE USING CAGED HAPTENS | PAFAH1B2, PAFAH1B3, PAF1 | BCHE 1870/4885BRD4 431/4885MALT1 3404/4885 |
| US-20080268462-A1 | Derivatives containing oxazole, pyrazole, thiazole, nitroaryl compound, benzofurazan, triterpene, urea, thiourea, rotenoid, coumarin or cyclolignan such as 4-(2-hydroxyphenyl)-1H-benzo[b][1,4]diazepine-2(3H)-one; multiplexed diagnostic assay for multiple targets in sample; antibodies; kits | HRH4, CRBN, NCDN | BCHE 1189/4885BRD4 56/4885MALT1 3256/4885 |
| US-20180120306-A1 | HAPTENS, HAPTEN CONJUGATES, COMPOSITIONS THEREOF AND METHOD FOR THEIR PREPARATION AND USE | CRBN, AHR, RORB | BCHE 1168/4885BRD4 654/4885MALT1 3155/4885 |
| US-20210221833-A1 | PROTEIN PROXIMITY ASSAY IN FORMALIN FIXED PARAFFIN EMBEDDED TISSUE USING CAGED HAPTENS | CD2BP2, CD68, CKAP4 | BCHE 2439/4885BRD4 1063/4885MALT1 1903/4885 |
| US-11345719-B2 | Protein proximity assay in formalin fixed paraffin embedded tissue using caged haptens | CD2BP2, CD68, CKAP4 | BCHE 2439/4885BRD4 1063/4885MALT1 1903/4885 |
| US-20100297725-A1 | Haptens, hapten conjugates, compositions thereof and method for their preparation and use | CRBN, GABBR1, SHBG | BCHE 1229/4885BRD4 423/4885MALT1 2567/4885 |
| US-20180186821-A1 | PROTEIN PROXIMITY ASSAY IN FORMALIN FIXED PAFFAFIN EMBEDDED TISSUE USING CAGED HAPTENS | PAFAH1B2, PAFAH1B3, PAF1 | BCHE 1870/4885BRD4 431/4885MALT1 3404/4885 |
| US-20190233447-A1 | PROTEIN PROXIMITY ASSAY IN FORMALIN FIXED PARAFFIN EMBEDDED TISSUE USING CAGED HAPTENS | CD2BP2, CD68, CKAP4 | BCHE 2439/4885BRD4 1063/4885MALT1 1903/4885 |
| US-11053266-B2 | Protein proximity assay in formalin fixed paffafin embedded tissue using caged haptens | PAFAH1B2, PAFAH1B3, PAF1 | BCHE 1870/4885BRD4 431/4885MALT1 3404/4885 |
| US-11092594-B2 | Haptens, hapten conjugates, compositions thereof and method for their preparation and use | CRBN, AHR, RORB | BCHE 1168/4885BRD4 654/4885MALT1 3155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.