Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24292004 | 0.81 | MEN1 (0.43) | MEN1KMT2ABRD4BCHECYP3A4 | |
| SCHEMBL24289992 | 0.80 | MEN1 (0.46) | MEN1KMT2ABRD4BCHECYP3A4 | |
| SCHEMBL24291844 | 0.71 | KDM4E (0.40) | MEN1KMT2ABRD4CYP3A4 | |
| SCHEMBL24289889 | 0.70 | KDM4E (0.40) | MEN1KMT2ABRD4BCHECYP3A4 | |
| SCHEMBL3531115 | 0.70 | CA12 (0.50) | BRD4BCHECYP3A4NPSR1 | |
| SCHEMBL6421336 | 0.69 | HDAC1 (0.48) | BRD4BCHECYP3A4DRD2HDAC3 | |
| SCHEMBL30875380 | 0.69 | BRD4 (0.42) | MEN1KMT2ABRD4BCHECYP3A4 | |
| SCHEMBL24289376 | 0.69 | BRD4 (0.48) | MEN1KMT2ABRD4BCHEDRD2 | |
| SCHEMBL24289990 | 0.68 | ALDH1A1 (0.46) | — | |
| SCHEMBL38658780 | 0.67 | ALDH1A1 (0.57) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022073469-A1 | COMPOUNDS AND METHODS OF TREATING CANCERS | CULLGEN (SHANGHAI) , INC. (CN) | 2022-04-14 | — | — | WO | disclosed |