SCHEMBL2429161

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2426297	0.95	PTGER4 (0.63)	PTGER4CYP1A2CYP2D6
	SCHEMBL13177155	0.92	PTGER4 (0.49)	PTGER4CYP1A2CYP2D6PPARDTHRA
	SCHEMBL12289187	0.88	PTGER4 (0.49)	PTGER4CYP1A2CYP2D6
	SCHEMBL2923324	0.86	PTGER4 (0.72)	PTGER4CYP1A2CYP2D6THRB
	SCHEMBL2936637	0.86	PTGER4 (0.58)	PTGER4CYP1A2CYP2D6THRATHRB
	SCHEMBL12289262	0.86	PTGER4 (0.52)	PTGER4CYP1A2CYP2D6
	SCHEMBL3225196	0.86	PTGER4 (0.55)	PTGER4CYP1A2CYP2D6CA2
	SCHEMBL2430351	0.85	PTGER4 (0.78)	PTGER4
	SCHEMBL2928448	0.84	PTGER4 (0.61)	PTGER4CYP1A2CYP2D6THRATHRB
	SCHEMBL2431846	0.84	PTGER4 (0.64)	PTGER4CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.