SCHEMBL24291985

SCHEMBL24291985

COC[C@H]1O[C@@H](n2cc(C)c(N)nc2=O)CC1OI

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ DNMT1 P26358 3/20 0.35
▸ ADRB1 P08588 1/20 0.35
▸ RNASE1 P07998 1/20 0.35
▸ TK1 P04183 1/20 0.34
▸ ALB P02768 1/20 0.34
▸ POLG P54098 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL68514 0.91 DNMT1 (0.36) DNMT1ADRB1RNASE1TK1ALB
SCHEMBL12590058 0.91 DNMT1 (0.36) DNMT1ADRB1RNASE1TK1ALB
SCHEMBL18573362 0.91 DNMT1 (0.36) DNMT1ADRB1RNASE1TK1ALB
SCHEMBL24229256 0.89 DNMT1 (0.37) DNMT1ADRB1ALBPOLG
SCHEMBL10036701 0.85 P2RY1 (0.36) DNMT1ADRB1TK1POLG
SCHEMBL26757510 0.85 POLG (0.40) TK1POLG
SCHEMBL26757229 0.85 POLG (0.40) TK1POLG
SCHEMBL21553506 0.85 P2RY1 (0.38) TK1POLG
SCHEMBL26757231 0.84 DNMT1 (0.48) DNMT1ADRB1TK1
SCHEMBL26757521 0.84 DNMT1 (0.48) DNMT1ADRB1TK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4261284-A1 STABLE TARGET-EDITING GUIDE RNA TO WHICH CHEMICALLY MODIFIED NUCLEIC ACID IS INTRODUCED Fukuoka University (JP) 2023-10-18 — — EP disclosed
EP-3981436-A1 STABLE TARGET-EDITING GUIDE RNA HAVING CHEMICALLY MODIFIED NUCLEIC ACID INTRODUCED THEREINTO Fukuoka University (JP) 2022-04-13 — — EP disclosed
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