Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 5/20 | 0.37 |
| ▸ | CA1 | P00915 | 5/20 | 0.37 |
| ▸ | CA2 | P00918 | 5/20 | 0.37 |
| ▸ | CA9 | Q16790 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24291379 | 0.94 | TDP1 (0.36) | TDP1MAOAMAOBCA12CA1 | |
| SCHEMBL24292009 | 0.78 | TDP1 (0.50) | TDP1MAOAMAOBCA12CA1 | |
| SCHEMBL24291378 | 0.69 | TDP1 (0.40) | TDP1MAOAMAOBCA12CA1 | |
| SCHEMBL25649015 | 0.69 | TDP1 (0.50) | TDP1MAOAMAOBCA12CA1 | |
| SCHEMBL19337989 | 0.69 | TDP1 (0.69) | TDP1MAOAMAOBCA12CA1 | |
| SCHEMBL25015343 | 0.69 | MAOA (0.53) | TDP1MAOAMAOBCA12CA1 | |
| SCHEMBL31729473 | 0.69 | TDP1 (0.51) | TDP1MAOAMAOBCA12CA1 | |
| SCHEMBL5162656 | 0.68 | TDP1 (0.85) | TDP1MAOAMAOBCA12CA1 | |
| SCHEMBL343629 | 0.68 | TDP1 (0.85) | TDP1MAOAMAOBCA12CA1 | |
| SCHEMBL134329 | 0.68 | TDP1 (0.85) | TDP1MAOAMAOBCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022073469-A1 | COMPOUNDS AND METHODS OF TREATING CANCERS | CULLGEN (SHANGHAI) , INC. (CN) | 2022-04-14 | — | — | WO | disclosed |