Trientine

Trientine

SCHEMBL242925

NCCNCCNCCN.O=P(O)(O)CP(=O)(O)O.O=P(O)(O)CP(=O)(O)O.O=P(O)(O)CP(=O)(O)O.O=P(O)(O)CP(=O)(O)O.O=P(O)(O)CP(=O)(O)O.O=P(O)(O)CP(=O)(O)O

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.55
CA6 P23280 4/20 0.55
CA7 P43166 4/20 0.55
CA9 Q16790 4/20 0.55
CA14 Q9ULX7 4/20 0.55
CA5B Q9Y2D0 4/20 0.55
LMNA P02545 3/20 0.55
CA2 P00918 3/20 0.55
CA4 P22748 3/20 0.55
CA5A P35218 3/20 0.55
TDP1 Q9NUW8 2/20 0.55
CA3 P07451 2/20 0.55
ALDH1A1 P00352 2/20 0.55
ALOX15 P16050 2/20 0.55
CA1 P00915 1/20 0.55
TP53 P04637 1/20 0.55
ANPEP P15144 1/20 0.54
KDM4E B2RXH2 2/20 0.52
HSD17B10 Q99714 2/20 0.50
MEN1 O00255 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Medronic Acid SCHEMBL833821 1.00 CA12 (0.55) CA12CA6CA7CA9CA14
Medronic Acid SCHEMBL3539311 1.00 CA12 (0.55) CA12CA6CA7CA9CA14
Trientine SCHEMBL9564313 1.00 CA12 (0.55) CA12CA6CA7CA9CA14
Medronic Acid SCHEMBL3537114 1.00 CA12 (0.55) CA12CA6CA7CA9CA14
Medronic Acid SCHEMBL9347974 0.97 ANPEP (0.56) CA12CA6CA7CA9CA14
Medronic Acid SCHEMBL3889431 0.97 ANPEP (0.56) CA12CA6CA7CA9CA14
Medronic Acid SCHEMBL1496457 0.97 ANPEP (0.56) CA12CA6CA7CA9CA14
Medronic Acid SCHEMBL220473 0.97 ANPEP (0.56) CA12CA6CA7CA9CA14
Medronic Acid SCHEMBL1138068 0.97 ANPEP (0.56) CA12CA6CA7CA9CA14
Medronic Acid SCHEMBL7081257 0.97 ANPEP (0.56) CA12CA6CA7CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7767636-B2 Nanoelectronic and microelectronic cleaning compositions MALLINCKRODT BAKER, INC. (US) 2010-08-03 US claimed
EP-1787168-B1 NON-AQUEOUS MICROELECTRONIC CLEANING COMPOSITIONS CONTAINING FRUCTOSE MALLINCKRODT BAKER INC (US) 2010-06-16 EP claimed
US-20080287333-A1 Non-Aqueous Microelectronic Cleaning Compositions Containing Fructose AVANTOR PERFORMANCE MATERIALS, INC. 2008-11-20 US claimed
EP-1787168-A1 NON-AQUEOUS MICROELECTRONIC CLEANING COMPOSITIONS CONTAINING FRUCTOSE Mallinckrodt Baker, Inc. (US) 2007-05-23 EP claimed
US-7101524-B2 Process for purifying sand GE BETZ, INC. (US) 2006-09-05 US claimed
WO-2006019402-A1 NON-AQUEOUS MICROELECTRONIC CLEANING COMPOSITIONS CONTAINING FRUCTOSE MALLINCKRODT BAKER, INC. (US) 2006-02-23 WO claimed
US-20030108463-A1 Process for purifying sand SMALL TERRENCE P (US) 2003-06-12 US claimed
WO-2002036504-A2 METHOD FOR CLEANING BLINDED FILTER MEDIA AND PREVENTING FILTER BLINDING GE BETZ, INC. (US) 2002-05-10 WO claimed
WO-2002022899-A2 REMOVAL OF BASE METALS DURING CYANIDE/CIP PROCESSING OF GOLD AND SILVER ORES GE BETZ, INC. (US) 2002-03-21 WO claimed
US-6265355-B1 CHELATING AGENT SELECTED FROM THE GROUP CONSISTING OF PHOSPHONIC ACIDS CONTAINING UP TO 8 PHOSPHONATE GROUPS AND DERIVATIVES AND AN AMINO CARBOXYLIC ACID CONTAINING FROM 1 TO 5 CARBOXYL GROUPS ATLANTIC RICHFIELD COMPANY 2001-07-24 US claimed
US-5498791-A AMINE OXIDE AND STABILIZER OF BICARBONATES AND CARBONATES ALBRIGHT & WILSON, LIMITED (GB) 1996-03-12 US claimed
EP-0553800-B1 Nitrosamine and nitrite inhibition ALBRIGHT & WILSON (GB) 1995-09-06 EP claimed
US-5442113-A Adding synergistic mixture of carbonate or bicarbonate and phosphonate to amine oxide product ALBRIGHT & WILSON LIMITED (GB) 1995-08-15 US claimed
EP-0553800-A2 Nitrosamine and nitrite inhibition ALBRIGHT & WILSON UK LIMITED (GB) 1993-08-04 EP claimed
US-4963157-A IMPREGNATING WITH BLEACH SOLUTION STABILIZED WITH HYDROXYACRYLIC ACID POLYMER AND ORGANIC PHOSPHONIC ACID NIPPON PEROXIDE CO., LTD. (JP) 1990-10-16 US claimed
WO-2024071285-A1 METHOD FOR MANUFACTURING SEMICONDUCTOR DEVICE, PROCESSING SOLUTION, AND KIT 富士フイルム株式会社 2024-04-04 WO disclosed
US-11767595-B2 Chemical liquid, chemical liquid container, and method for treating substrate FUJIFILM CORPORATION (JP) 2023-09-26 US disclosed
EP-0037146-B1 DETERGENT BLEACH COMPOSITIONS UNILEVER N.V. (NL) 1984-06-13 EP disclosed
US-4325828-A PEROXYACIDS, PEROXIDE LEVER BROTHERS COMPANY (US) 1982-04-20 US disclosed
EP-0037146-A1 Detergent bleach compositions UNILEVER N.V. (NL) 1981-10-07 EP disclosed