Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CD81 | P60033 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2438566 | 0.94 | NR1H2 (0.32) | HSD17B10NR1H2CD81 | |
| SCHEMBL2434958 | 0.87 | NR1H2 (0.33) | ITGA4NR1H2 | |
| SCHEMBL5364156 | 0.85 | ITGA4 (0.31) | ITGA4NR1H2 | |
| SCHEMBL5364147 | 0.85 | ITGA4 (0.31) | ITGA4NR1H2 | |
| SCHEMBL2435163 | 0.83 | NR1H2 (0.37) | ITGA4NR1H2 | |
| SCHEMBL12327705 | 0.83 | ITGA4 (0.33) | ITGA4NR1H2 | |
| SCHEMBL2434882 | 0.82 | NR1H2 (0.36) | ITGA4NR1H2 | |
| SCHEMBL2437574 | 0.82 | NR1H2 (0.34) | NR1H2 | |
| SCHEMBL2429319 | 0.81 | ITGA4 (0.30) | ITGA4 | |
| SCHEMBL2432189 | 0.81 | ITGA4 (0.30) | ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1346982-B1 | VLA-4 INHIBITORS | DAIICHI SEIYAKU CO (JP) | 2011-09-14 | — | — | EP | disclosed |