Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4398259 | 0.95 | ACE (0.31) | ABHD6 | |
| SCHEMBL2433593 | 0.90 | ABHD6 (0.32) | ABHD6 | |
| SCHEMBL8227815 | 0.88 | ABHD6 (0.34) | ABHD6CYP19A1 | |
| SCHEMBL2430723 | 0.87 | ABHD6 (0.31) | ABHD6CYP19A1 | |
| SCHEMBL4297844 | 0.87 | CYP19A1 (0.32) | CYP19A1 | |
| Trifluoroacetic Acid SCHEMBL2433587 | 0.87 | ABHD6 (0.30) | ABHD6 | |
| SCHEMBL8229439 | 0.82 | CYP19A1 (0.33) | CYP19A1 | |
| SCHEMBL8227246 | 0.81 | ABHD6 (0.38) | ABHD6CYP19A1 | |
| SCHEMBL8231179 | 0.81 | ABHD6 (0.32) | ABHD6CYP19A1 | |
| SCHEMBL16418965 | 0.81 | ABHD6 (0.34) | ABHD6CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8314062-B2 | Macrocyclic compounds as antiviral agents | INSTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2012-11-20 | — | — | US | disclosed |
| EP-2041159-B1 | MACROCYCLIC COMPOUNDS AS ANTIVIRAL AGENTS | ANGELETTI P IST RICHERCHE BIO (IT) | 2011-09-28 | — | — | EP | disclosed |
| US-20090312241-A1 | Macrocyclic Compounds as Antiviral Agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2009-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312241-A1 | Macrocyclic Compounds as Antiviral Agents | ZC3HAV1, ZC3HAV1L, HAVCR2 | ABHD6 3780/4885CYP19A1 2087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.