Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 5/20 | 0.70 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.41 |
| ▸ | ABAT | P80404 | 2/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | GRM8 | O00222 | 1/20 | 0.38 |
| ▸ | GRM6 | O15303 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5844291 | 0.86 | GABRR1 (0.94) | GABRR1GABRR2SLC1A2CYP2C19CYP2C9 | |
| SCHEMBL5492237 | 0.84 | GABRR1 (0.62) | GABRR1GABRR2ABATSLC1A2CYP2C19 | |
| SCHEMBL9512745 | 0.83 | — | — | |
| SCHEMBL31520046 | 0.83 | — | — | |
| SCHEMBL4037202 | 0.83 | — | — | |
| SCHEMBL296233 | 0.83 | — | — | |
| SCHEMBL667571 | 0.83 | — | — | |
| SCHEMBL1963027 | 0.83 | GABRR1 (0.58) | GABRR1GABRR2SLC1A2CYP2C19CYP2C9 | |
| SCHEMBL31520043 | 0.83 | — | — | |
| SCHEMBL11938161 | 0.83 | GABRR1 (0.58) | GABRR1ABATSLC1A2CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022074391-A1 | COMPOUNDS INHIBITORS OF METTL3 | STORM THERAPEUTICS LIMITED (GB) | 2022-04-14 | — | — | WO | disclosed |