Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.61 |
| ▸ | MEN1 | O00255 | 8/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | BRD4 | O60885 | 1/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | MB | P02144 | 1/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.55 |
| ▸ | CA3 | P07451 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | RARG | P13631 | 1/20 | 0.55 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2968894 | 0.87 | MEN1 (0.63) | KMT2AMEN1MAPTKDM4ENPSR1 | |
| SCHEMBL25145166 | 0.86 | MEN1 (0.61) | KMT2AMEN1MAPTKDM4ENPSR1 | |
| SCHEMBL21862103 | 0.84 | MEN1 (0.60) | KMT2AMEN1MAPTKDM4ENPSR1 | |
| SCHEMBL19514709 | 0.83 | MEN1 (0.61) | KMT2AMEN1MAPTKDM4ENPSR1 | |
| SCHEMBL19513381 | 0.83 | MEN1 (0.58) | KMT2AMEN1MAPTKDM4ENPSR1 | |
| SCHEMBL22106658 | 0.83 | KMT2A (0.58) | KMT2AMEN1MAPTKDM4ENPSR1 | |
| SCHEMBL19491612 | 0.83 | KMT2A (0.58) | KMT2AMEN1MAPTKDM4ENPSR1 | |
| SCHEMBL3150538 | 0.81 | SMN1; SMN2 (0.60) | KMT2AMEN1MAPTKDM4ENPSR1 | |
| SCHEMBL19042827 | 0.81 | MEN1 (0.58) | KMT2AMEN1MAPTKDM4ENPSR1 | |
| SCHEMBL17721364 | 0.81 | MEN1 (0.57) | KMT2AMEN1MAPTKDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3642198-B1 | SMALL MOLECULE MODULATORS OF HUMAN STING | CURADEV PHARMA LTD (GB) | 2022-03-16 | — | — | EP | disclosed |