Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | BRD4 | O60885 | 1/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | MB | P02144 | 1/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.55 |
| ▸ | CA3 | P07451 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | RARG | P13631 | 1/20 | 0.55 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2968894 | 0.87 | MEN1 (0.63) | MEN1KMT2AMAPTKDM4ENPSR1 | |
| SCHEMBL24296352 | 0.86 | KMT2A (0.61) | MEN1KMT2AMAPTKDM4ENPSR1 | |
| SCHEMBL21862103 | 0.84 | MEN1 (0.60) | MEN1KMT2AMAPTKDM4ENPSR1 | |
| SCHEMBL19514709 | 0.83 | MEN1 (0.61) | MEN1KMT2AMAPTKDM4ENPSR1 | |
| SCHEMBL19491612 | 0.83 | KMT2A (0.58) | MEN1KMT2AMAPTKDM4ENPSR1 | |
| SCHEMBL22106658 | 0.83 | KMT2A (0.58) | MEN1KMT2AMAPTKDM4ENPSR1 | |
| SCHEMBL19513381 | 0.83 | MEN1 (0.58) | MEN1KMT2AMAPTKDM4ENPSR1 | |
| SCHEMBL21163456 | 0.81 | APP (0.46) | MEN1KMT2AMAPTKDM4ENPSR1 | |
| SCHEMBL3150538 | 0.81 | SMN1; SMN2 (0.60) | MEN1KMT2AMAPTKDM4ENPSR1 | |
| SCHEMBL17721364 | 0.81 | MEN1 (0.57) | MEN1KMT2AMAPTKDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12036286-B2 | Selective drug release from internalized conjugates of biologically active compounds | SEAGEN INC. (US) | 2024-07-16 | — | — | US | disclosed |
| EP-3838893-B1 | LINKER, ANTIBODY-DRUG CONJUGATE INCLUDING SAME, AND USE THEREOF | ACAD OF MILITARY MEDICAL SCIENCES (CN) | 2023-04-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12036286-B2 | Selective drug release from internalized conjugates of biologically active compounds | CTSB, CTSE, CTSZ | MEN1 1450/4885KMT2A 3707/4885MAPT 2868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.