Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 14/20 | 0.59 |
| ▸ | BTK | Q06187 | 3/20 | 0.51 |
| ▸ | AR | P10275 | 5/20 | 0.51 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.49 |
| ▸ | CDK9 | P50750 | 1/20 | 0.48 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.46 |
| ▸ | IRAK3 | Q9Y616 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | PLK4 | O00444 | 1/20 | 0.45 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24299483 | 0.89 | CRBN (0.62) | CRBNBTKARDDB1CDK9 | |
| SCHEMBL29597385 | 0.89 | CRBN (0.55) | CRBNBTKARDDB1CDK9 | |
| SCHEMBL23117898 | 0.88 | CRBN (0.58) | CRBNBTKARDDB1CDK9 | |
| SCHEMBL29822185 | 0.88 | CRBN (0.58) | CRBNBTKARDDB1CDK9 | |
| SCHEMBL24299348 | 0.87 | CRBN (0.66) | CRBNBTKARDDB1CDK9 | |
| SCHEMBL29986989 | 0.87 | CRBN (0.66) | CRBNBTKARDDB1CDK9 | |
| SCHEMBL24299443 | 0.86 | CRBN (0.59) | CRBNESR1 | |
| SCHEMBL24299390 | 0.86 | CRBN (0.52) | CRBNESR1 | |
| SCHEMBL31447942 | 0.86 | CRBN (0.62) | CRBNBTKARDDB1CDK9 | |
| SCHEMBL24298644 | 0.85 | CRBN (0.53) | CRBNBTKARDDB1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022048605-A1 | HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, INTERMEDIATE, COMPOSITION, AND APPLICATIONS | 南昌奥瑞药业有限公司 | 2022-03-10 | — | — | WO | disclosed |