Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 3/20 | 0.34 |
| ▸ | FEN1 | P39748 | 3/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 3/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24300879 | 0.98 | ALOX5AP (0.34) | ALOX5APFEN1APPRARBRARA | |
| SCHEMBL24300870 | 0.96 | RARB (0.34) | ALOX5APFEN1RARBRARARARG | |
| SCHEMBL24300931 | 0.91 | APP (0.35) | ALOX5APFEN1APPFFAR4 | |
| SCHEMBL24300874 | 0.91 | ALOX5AP (0.37) | ALOX5APFEN1APPRARBRARA | |
| SCHEMBL24300967 | 0.89 | FEN1 (0.35) | ALOX5APFEN1APPFFAR4 | |
| SCHEMBL24300651 | 0.87 | MPL (0.32) | APP | |
| SCHEMBL24300947 | 0.86 | NAAA (0.33) | ALOX5APFEN1APP | |
| SCHEMBL24300683 | 0.85 | APP (0.37) | ALOX5APFEN1APP | |
| SCHEMBL24300875 | 0.85 | FEN1 (0.33) | ALOX5APFEN1RARBRARARARG | |
| SCHEMBL24300658 | 0.84 | MPL (0.32) | ALOX5APFEN1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022068499-A1 | THIOPHENE-CONTAINING LIQUID CRYSTAL COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 北京八亿时空液晶科技股份有限公司 | 2022-04-07 | — | — | WO | disclosed |