Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 5/20 | 0.50 |
| ▸ | TACR3 | P29371 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 2/20 | 0.48 |
| ▸ | MMP8 | P22894 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24301899 | 0.95 | TACR1 (0.54) | TACR1TACR3MMP9MMP8MMP2 | |
| SCHEMBL22354581 | 0.94 | TACR1 (0.52) | TACR1TACR3MMP9MMP8MMP2 | |
| SCHEMBL22355217 | 0.94 | TACR1 (0.52) | TACR1TACR3MMP9MMP8MMP2 | |
| SCHEMBL24301394 | 0.93 | TACR1 (0.51) | TACR1KMT2AMAPTKDM4EMEN1 | |
| SCHEMBL24301900 | 0.93 | TACR1 (0.49) | TACR1TACR3MMP9MMP8MMP2 | |
| SCHEMBL24301264 | 0.92 | TACR1 (0.49) | TACR1TACR3MMP9MMP8MMP2 | |
| SCHEMBL24301263 | 0.92 | MMP9 (0.50) | TACR1TACR3MMP9MMP8MMP2 | |
| SCHEMBL24301259 | 0.92 | ERAP2 (0.51) | TACR1TACR3MMP9MMP8MMP2 | |
| SCHEMBL24301420 | 0.92 | ERAP2 (0.51) | TACR1TACR3MMP9MMP8MMP2 | |
| SCHEMBL24301905 | 0.92 | ACE (0.50) | TACR1TACR3MMP9MMP8MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078462-A1 | NOVEL GLUTAMINE ANALOGS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-04-21 | — | — | WO | disclosed |