SCHEMBL24304364

SCHEMBL24304364

CCCCCCCCCCCCCCOCCCCOP(=O)(O)OC[C@H]1O[C@@](C#N)(c2ccc3c(N)ncnn23)[C@H](O)[C@@H]1O

nearest known ligand 0.71

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ TMPRSS2 O15393 1/20 0.42
▸ ADK P55263 6/20 0.38
▸ POLRMT O00411 1/20 0.35
▸ FGFR1 P11362 1/20 0.34
▸ TRPM2 O94759 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25967624 1.00 TMPRSS2 (0.42) TMPRSS2ADKPOLRMTFGFR1TRPM2
SCHEMBL25968060 1.00 TMPRSS2 (0.42) TMPRSS2ADKPOLRMTFGFR1TRPM2
SCHEMBL24304404 0.99 TMPRSS2 (0.42) TMPRSS2ADKPOLRMTFGFR1TRPM2
SCHEMBL24339531 0.99 TMPRSS2 (0.42) TMPRSS2ADKPOLRMTFGFR1TRPM2
SCHEMBL24305335 0.99 TMPRSS2 (0.42) TMPRSS2ADKPOLRMTFGFR1TRPM2
SCHEMBL24304406 0.99 TMPRSS2 (0.42) TMPRSS2ADKPOLRMTFGFR1TRPM2
SCHEMBL24304741 0.99 TMPRSS2 (0.42) TMPRSS2ADKPOLRMTFGFR1TRPM2
SCHEMBL24304701 0.99 TMPRSS2 (0.42) TMPRSS2ADKPOLRMTFGFR1TRPM2
SCHEMBL24304414 0.99 TMPRSS2 (0.42) TMPRSS2ADKPOLRMTFGFR1TRPM2
SCHEMBL24339481 0.98 TMPRSS2 (0.42) TMPRSS2ADKPOLRMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12030904-B2 Phospholipid compounds and uses thereof GILEAD SCIENCES, INC. (US) 2024-07-09 — — US disclosed
US-20230250117-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2023-08-10 — — US disclosed
EP-4200301-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. (US) 2023-06-28 — — EP disclosed
US-20220081455-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2022-03-17 — — US disclosed
WO-2022046631-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. (US) 2022-03-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12030904-B2 Phospholipid compounds and uses thereof PHOSPHO1, SGMS2, SGMS1 TMPRSS2 310/4885ADK 1238/4885POLRMT 371/4885
US-20230250117-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF PHOSPHO1, SGMS2, SGMS1 TMPRSS2 310/4885ADK 1238/4885POLRMT 371/4885
US-20220081455-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF PHOSPHO1, SGMS2, SGMS1 TMPRSS2 310/4885ADK 1238/4885POLRMT 371/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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