SCHEMBL24306809

SCHEMBL24306809

IC1CN2CCCC2CN1

nearest known ligand 0.39

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2801366 0.75 HTR6 (0.39) HTR6
SCHEMBL14395626 0.75 HTR6 (0.39) HTR6
SCHEMBL597625 0.75 HTR6 (0.39) HTR6
SCHEMBL26767154 0.75 HTR6 (0.39) HTR6
SCHEMBL10073208 0.75 HTR6 (0.39) HTR6
SCHEMBL10743870 0.75 HTR6 (0.39) HTR6
SCHEMBL25270380 0.71 HTR6 (0.36) HTR6
SCHEMBL8239226 0.71 HTR6 (0.36) HTR6
SCHEMBL24179707 0.71 HTR6 (0.36) HTR6
SCHEMBL336904 0.71 HTR6 (0.36) HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4289852-A1 5,6-DIHYDROTHIENO[3,4-H]QUINAZOLINE COMPOUND Medshine Discovery Inc. (CN) 2023-12-13 EP disclosed
EP-4219461-A1 TETRAHYDROISOQUINOLINE DERIVATIVE AND USE THEREOF Medshine Discovery Inc. (CN) 2023-08-02 EP disclosed
WO-2022063094-A1 TETRAHYDROISOQUINOLINE DERIVATIVE AND USE THEREOF 南京明德新药研发有限公司 2022-03-31 WO disclosed