⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3779668 | 0.85 | GAA (0.46) | — | |
| SCHEMBL19625079 | 0.83 | GAA (0.41) | — | |
| SCHEMBL19610492 | 0.81 | GAA (0.40) | — | |
| SCHEMBL10991170 | 0.74 | — | — | |
| SCHEMBL30461817 | 0.72 | — | — | |
| SCHEMBL19199368 | 0.70 | CYP11B1 (0.38) | — | |
| SCHEMBL9804852 | 0.69 | GAA (0.33) | — | |
| SCHEMBL36368 | 0.67 | PARL (0.43) | — | |
| SCHEMBL10729759 | 0.66 | — | — | |
| SCHEMBL7736371 | 0.65 | PARL (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0093376-B2 | 1-Sulfo-2-azetidinone derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-04-07 | — | — | EP | claimed |
| EP-0093376-B1 | 1-SULFO-2-AZETIDINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1990-03-21 | — | — | EP | claimed |
| EP-0100041-B1 | 1-SULFO-2-AZETIDINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1986-10-22 | — | — | EP | claimed |
| EP-0095778-B1 | 2-OXO-1-AZETIDINESULFONIC ACID DERIVATIVES, PROCESS FOR PRODUCTION THEREOF, AND USE THEREOF | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1986-07-30 | — | — | EP | claimed |
| US-4572801-A | LACTAMASE ENZYME INHIBITORS, MICROBIOCIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1986-02-25 | — | — | US | claimed |
| EP-0100041-A1 | 1-Sulfo-2-azetidinone derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1984-02-08 | — | — | EP | claimed |
| EP-0096297-A2 | Process for the preparation of 1-sulfo-2-oxoazetidine derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1983-12-21 | — | — | EP | claimed |
| EP-0093376-A2 | 1-Sulfo-2-azetidinone derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1983-11-09 | — | — | EP | claimed |
| EP-0053387-A1 | Method of preparing 1-sulfo-2-oxoazetidine derivatives and intermediates therefor | Takeda Chemical Industries, Ltd. (JP) | 1982-06-09 | — | — | EP | claimed |
| JP-58210060-A | — | — | None | — | — | JP | disclosed |
| JP-56133260-A | — | — | None | — | — | JP | disclosed |
| JP-57098258-A | — | — | None | — | — | JP | disclosed |
| JP-59020281-A | — | — | None | — | — | JP | disclosed |
| JP-58189176-A | — | — | None | — | — | JP | disclosed |
| EP-0050965-A1 | Beta-lactamase inhibitory composition | Takeda Chemical Industries, Ltd. (JP) | 1982-05-05 | — | — | EP | disclosed |
| JP-S56133260-A | AZETIDINE DERIVATIVE AND ITS PREPARATION | TAKEDA CHEM IND LTD | 1981-10-19 | — | — | JP | disclosed |
| EP-0021678-A1 | 1-Sulpho-2-oxoazetidine derivatives, their production and pharmaceutical compositions thereof | Takeda Chemical Industries, Ltd. (JP) | 1981-01-07 | — | — | EP | disclosed |
| EP-0021678-A1 | 1-Sulpho-2-oxoazetidine derivatives, their production and pharmaceutical compositions thereof | Takeda Chemical Industries, Ltd. (JP) | 1981-01-07 | — | — | EP | disclosed |
| EP-0021678-A1 | 1-Sulpho-2-oxoazetidine derivatives, their production and pharmaceutical compositions thereof | Takeda Chemical Industries, Ltd. (JP) | 1981-01-07 | — | — | EP | disclosed |
| JP-S55164672-A | AZETIDINE DERIVATIVE AND ITS PREPARATION | TAKEDA CHEM IND LTD | 1980-12-22 | — | — | JP | disclosed |