Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25698883 | 0.96 | TSHR (0.41) | TSHRMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL13311547 | 0.92 | MEN1 (0.48) | TSHRMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL2789982 | 0.88 | TDP1 (0.51) | TSHRMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL16924939 | 0.87 | ALDH1A1 (0.47) | TSHRMEN1KMT2AALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL16908991 | 0.85 | ALDH1A1 (0.50) | TSHRMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL11885243 | 0.84 | MEN1 (0.40) | TSHRMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL16081648 | 0.84 | MEN1 (0.42) | TSHRMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL24321681 | 0.84 | TSHR (0.50) | TSHRMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL19133112 | 0.83 | EPHX2 (0.43) | TSHRMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL22349961 | 0.82 | MEN1 (0.41) | TSHRMEN1KMT2AALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078470-A1 | METHODS AND COMPOSITIONS FOR TARGETED PROTEIN DEGRADATION | RANOK THERAPEUTICS (HANGZHOU) CO. LTD. (CN) | 2022-04-21 | — | — | WO | disclosed |