Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 17/20 | 0.84 |
| ▸ | DCLK1 | O15075 | 16/20 | 0.84 |
| ▸ | MAPK7 | Q13164 | 15/20 | 0.84 |
| ▸ | BRD4 | O60885 | 3/20 | 0.84 |
| ▸ | TNK2 | Q07912 | 3/20 | 0.84 |
| ▸ | TNK1 | Q13470 | 2/20 | 0.84 |
| ▸ | DCLK2 | Q8N568 | 2/20 | 0.84 |
| ▸ | PLK4 | O00444 | 1/20 | 0.84 |
| ▸ | PI4KA | P42356 | 1/20 | 0.84 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.84 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.84 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.84 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.84 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.84 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.84 |
| ▸ | GAK | O14976 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29582720 | 0.93 | LRRK2 (0.83) | LRRK2DCLK1MAPK7BRD4TNK2 | |
| SCHEMBL24334887 | 0.93 | LRRK2 (0.83) | LRRK2DCLK1MAPK7BRD4TNK2 | |
| Hydrochloric Acid SCHEMBL29583567 | 0.93 | LRRK2 (0.82) | LRRK2DCLK1MAPK7BRD4TNK2 | |
| SCHEMBL619295 | 0.92 | LRRK2 (1.00) | LRRK2DCLK1MAPK7BRD4TNK2 | |
| SCHEMBL29372331 | 0.92 | LRRK2 (1.00) | LRRK2DCLK1MAPK7BRD4TNK2 | |
| SCHEMBL29356878 | 0.92 | LRRK2 (1.00) | LRRK2DCLK1MAPK7BRD4TNK2 | |
| SCHEMBL17721077 | 0.91 | LRRK2 (0.87) | LRRK2DCLK1MAPK7BRD4TNK2 | |
| SCHEMBL24307411 | 0.91 | LRRK2 (0.79) | LRRK2DCLK1MAPK7BRD4TNK2 | |
| SCHEMBL27196822 | 0.90 | LRRK2 (0.75) | LRRK2DCLK1MAPK7BRD4TNK2 | |
| Trifluoroacetic Acid SCHEMBL30842197 | 0.89 | LRRK2 (0.89) | LRRK2DCLK1MAPK7BRD4TNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240124460-A1 | METHODS AND COMPOSITIONS FOR TARGETED PROTEIN DEGRADATION | RANOK THERAPEUTICS (HANGZHOU) CO. LTD. (CN) | 2024-04-18 | — | — | US | disclosed |
| EP-4229061-A1 | METHODS AND COMPOSITIONS FOR TARGETED PROTEIN DEGRADATION | Ranok Therapeutics (Hangzhou) Co. Ltd. (CN) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022078350-A1 | METHODS AND COMPOSITIONS FOR TARGETED PROTEIN DEGRADATION | RANOK THERAPEUTICS (HANGZHOU) CO. LTD. (CN) | 2022-04-21 | — | — | WO | disclosed |
| WO-2022078350-A1 | METHODS AND COMPOSITIONS FOR TARGETED PROTEIN DEGRADATION | RANOK THERAPEUTICS (HANGZHOU) CO. LTD. (CN) | 2022-04-21 | — | — | WO | disclosed |
| WO-2022078470-A1 | METHODS AND COMPOSITIONS FOR TARGETED PROTEIN DEGRADATION | RANOK THERAPEUTICS (HANGZHOU) CO. LTD. (CN) | 2022-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240124460-A1 | METHODS AND COMPOSITIONS FOR TARGETED PROTEIN DEGRADATION | PSMG3, PSMC2, PSMA6 | LRRK2 1277/4885DCLK1 2928/4885MAPK7 1599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.