SCHEMBL2430852

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2430579	1.00	GRM4 (0.44)	GRM4JAK1NPC1RAB9APKM
	SCHEMBL13630802	0.93	GRM4 (0.44)	GRM4JAK1NPC1RAB9APKM
	SCHEMBL2432673	0.92	PTPN1 (0.46)	GRM4JAK1NPC1RAB9APKM
	SCHEMBL2432670	0.92	PTPN1 (0.46)	GRM4JAK1NPC1RAB9APKM
	SCHEMBL2432741	0.90	RAB9A (0.42)	GRM4NPC1RAB9APKMTP53
	SCHEMBL2432736	0.90	RAB9A (0.42)	GRM4NPC1RAB9APKMTP53
	SCHEMBL2430828	0.90	SMN1; SMN2 (0.42)	JAK1NPC1RAB9ATP53ALDH1A1
	SCHEMBL2432684	0.90	KMT2A (0.39)	GRM4JAK1DGAT1
	SCHEMBL2430826	0.90	SMN1; SMN2 (0.42)	JAK1NPC1RAB9ATP53ALDH1A1
	SCHEMBL2432681	0.90	KMT2A (0.39)	GRM4JAK1DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.