Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE6D | O43924 | 12/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28480818 | 0.86 | PDE6D (0.71) | PDE6DALDH1A1SMN1; SMN2 | |
| SCHEMBL28480531 | 0.79 | PDE6D (0.46) | PDE6DALDH1A1 | |
| SCHEMBL6403440 | 0.77 | PDE6D (0.63) | PDE6DALDH1A1POLB | |
| SCHEMBL28482876 | 0.77 | PDE6D (0.78) | PDE6DSMN1; SMN2 | |
| SCHEMBL24309074 | 0.77 | PDE6D (0.59) | PDE6DSMN1; SMN2 | |
| SCHEMBL10647039 | 0.75 | MC4R (0.56) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL28477079 | 0.73 | PDE6D (0.64) | PDE6DSMN1; SMN2 | |
| SCHEMBL6405075 | 0.73 | TDP1 (0.72) | ALDH1A1SMN1; SMN2POLBRECQL | |
| SCHEMBL28478740 | 0.72 | PDE6D (1.00) | PDE6D | |
| SCHEMBL28489551 | 0.72 | PDE6D (0.70) | PDE6DALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022079226-A1 | INHIBITORS OF PDEDELTA | UNIVERSITÉ DU LUXEMBOURG (LU) | 2022-04-21 | — | — | WO | disclosed |