Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE6D | O43924 | 12/20 | 0.63 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28480818 | 0.89 | PDE6D (0.71) | PDE6DTSHRHTTALDH1A1SIRT2 | |
| SCHEMBL6406141 | 0.86 | OPRK1 (0.59) | PDE6DOPRK1TP53POLBALOX15 | |
| SCHEMBL6411912 | 0.82 | OPRK1 (0.64) | PDE6DOPRK1TP53POLBALOX15 | |
| SCHEMBL28482876 | 0.82 | PDE6D (0.78) | PDE6D | |
| SCHEMBL6408179 | 0.81 | OPRK1 (0.53) | PDE6DOPRK1TP53POLBALOX15 | |
| SCHEMBL28489551 | 0.77 | PDE6D (0.70) | PDE6DTSHRALDH1A1 | |
| SCHEMBL28478740 | 0.77 | PDE6D (1.00) | PDE6D | |
| SCHEMBL24308992 | 0.77 | PDE6D (0.55) | PDE6DPOLBALDH1A1 | |
| SCHEMBL28477079 | 0.77 | PDE6D (0.64) | PDE6D | |
| SCHEMBL4206615 | 0.76 | HTT (0.66) | OPRK1TP53POLBALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | PDE6D 3331/4885OPRK1 4243/4885TP53 1524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.