SCHEMBL24309151

SCHEMBL24309151

c1ccc(N(c2ccccc2)c2ccc(-c3cccc(N(c4ccccc4)c4ccc(N(c5ccccc5)c5ccccc5)cc4)c3)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
CYP3A4 P08684 2/20 0.48
CYP2C9 P11712 2/20 0.48
KDM4E B2RXH2 2/20 0.48
MAPT P10636 2/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2D6 P10635 1/20 0.48
CYP2C19 P33261 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
MGLL Q99685 2/20 0.43
MAOA P21397 1/20 0.43
APP P05067 1/20 0.42
ALOX5 P09917 1/20 0.41
ACMSD Q8TDX5 2/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
CRHBP P24387 1/20 0.41
ATM Q13315 1/20 0.41
CRHR2 Q13324 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2604762 1.00 ALDH1A1 (0.48) ALDH1A1L3MBTL1CYP3A4CYP2C9KDM4E
SCHEMBL17014964 1.00 ALDH1A1 (0.48) ALDH1A1L3MBTL1CYP3A4CYP2C9KDM4E
SCHEMBL16305494 1.00 ALDH1A1 (0.48) ALDH1A1L3MBTL1CYP3A4CYP2C9KDM4E
SCHEMBL22355482 1.00 ALDH1A1 (0.48) ALDH1A1L3MBTL1CYP3A4CYP2C9KDM4E
SCHEMBL13020716 1.00 ALDH1A1 (0.48) ALDH1A1L3MBTL1CYP3A4CYP2C9KDM4E
SCHEMBL23108823 1.00 ALDH1A1 (0.48) ALDH1A1L3MBTL1CYP3A4CYP2C9KDM4E
SCHEMBL13854551 1.00 ALDH1A1 (0.48) ALDH1A1L3MBTL1CYP3A4CYP2C9KDM4E
SCHEMBL23108813 1.00 ALDH1A1 (0.48) ALDH1A1L3MBTL1CYP3A4CYP2C9KDM4E
SCHEMBL21365004 1.00 ALDH1A1 (0.48) ALDH1A1L3MBTL1CYP3A4CYP2C9KDM4E
SCHEMBL18417839 1.00 ALDH1A1 (0.48) ALDH1A1L3MBTL1CYP3A4CYP2C9KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11289654-B2 Polymers containing furanyl crosslinkable groups and uses thereof GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) 2022-03-29 US disclosed