Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24310784 | 0.92 | MAP3K7 (0.32) | CDK1MAP3K7MAPK1MAP2K1 | |
| SCHEMBL24310420 | 0.83 | SCD (0.33) | MAP3K7MAPK1MAP2K1SCD | |
| SCHEMBL24310413 | 0.82 | CTSC (0.35) | — | |
| SCHEMBL24310085 | 0.81 | CDK1 (0.30) | CDK1 | |
| SCHEMBL24309901 | 0.80 | IGF1R (0.33) | MAP3K7MAPK1MAP2K1SCD | |
| SCHEMBL24309646 | 0.80 | HTR1A (0.37) | CDK1MAP3K7MAPK1MAP2K1 | |
| SCHEMBL29566971 | 0.80 | HTR1A (0.37) | CDK1MAP3K7MAPK1MAP2K1 | |
| SCHEMBL24310590 | 0.80 | IGF1R (0.31) | — | |
| SCHEMBL24309917 | 0.78 | MAPK14 (0.33) | — | |
| SCHEMBL24310486 | 0.78 | JAK2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022076627-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-04-14 | — | — | WO | disclosed |