Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT4 | P35916 | 2/20 | 0.31 |
| ▸ | KDR | P35968 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24310812 | 0.86 | — | — | |
| SCHEMBL24309610 | 0.84 | — | — | |
| SCHEMBL24309576 | 0.84 | JAK2 (0.33) | — | |
| SCHEMBL29567029 | 0.82 | HTR1A (0.35) | FLT4KDRCNR2 | |
| SCHEMBL24309606 | 0.82 | HTR1A (0.35) | FLT4KDRCNR2 | |
| SCHEMBL24310386 | 0.81 | KDM4E (0.30) | — | |
| SCHEMBL24309710 | 0.78 | FLT4 (0.30) | FLT4KDR | |
| SCHEMBL24310222 | 0.78 | KDM5B (0.30) | — | |
| SCHEMBL24310486 | 0.75 | JAK2 (0.32) | — | |
| SCHEMBL24309815 | 0.74 | JAK2 (0.34) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022076627-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-04-14 | — | — | WO | disclosed |