⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1169597 | 0.98 | SLC6A3 (0.40) | — | |
| Hydrochloric Acid SCHEMBL246103 | 0.98 | — | — | |
| SCHEMBL34463069 | 0.82 | — | — | |
| SCHEMBL13142435 | 0.80 | SLC6A3 (0.43) | — | |
| SCHEMBL18673935 | 0.80 | SLC6A3 (0.43) | — | |
| SCHEMBL11561789 | 0.79 | SLC6A3 (0.37) | — | |
| SCHEMBL1398205 | 0.78 | — | — | |
| SCHEMBL1107383 | 0.76 | — | — | |
| SCHEMBL4654099 | 0.76 | — | — | |
| SCHEMBL3695252 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4108994-A | 5-THIAZOLE-METHANE-AMINES, AND THEIR USE AS ANTILIPOLYTICS | ROUSSEL UCLAF (FR) | 1978-08-22 | — | — | US | claimed |
| EP-4725942-A1 | COMPOUNDS ACTIVE ON CYCLIN D1 PATHWAY AND THEIR USE | Sibylla Biotech S.p.A. (IT) | 2026-04-15 | — | — | EP | disclosed |
| EP-4050005-B1 | BICYCLIC BET BROMODOMAIN INHIBITORS AND USES THEREOF | CONVERGENE LLC (US) | 2024-12-25 | — | — | EP | disclosed |
| WO-2024067304-A1 | COMPOUND WITH INHIBITORY ACTIVITY AGAINST SIGMA2 AND 5HT2A AND USE | 瀚远医药有限公司 | 2024-04-04 | — | — | WO | disclosed |
| US-20240083908-A1 | TETRAHYDROTHIENOPYRIMIDINESULFONAMIDE COMPOUNDS | ALIVEXIS, INC. (JP) | 2024-03-14 | — | — | US | disclosed |
| US-20240025890-A1 | HEPATITIS B CORE PROTEIN MODULATORS | ASSEMBLY BIOSCIENCES INC (US) | 2024-01-25 | — | — | US | disclosed |
| US-11814376-B2 | Hepatitis b core protein modulators | ASSEMBLY BIOSCIENCES, INC. (US) | 2023-11-14 | — | — | US | disclosed |
| US-20230355638-A1 | Cyclopentathiophene Carboxamide Derivatives as Platelet Activating Factor Receptor Antagonists | BOEHRINGER INGELHEIM INT (DE) | 2023-11-09 | — | — | US | disclosed |
| EP-4269415-A1 | TETRAHYDRO THIENOPYRIDINE SULFONAMIDE COMPOUND | Modulus Discovery, Inc. (JP) | 2023-11-01 | — | — | EP | disclosed |
| US-11766443-B2 | Cyclopentathiophene carboxamide derivatives as platelet activating factor receptor antagonists | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-09-26 | — | — | US | disclosed |
| EP-0665222-A1 | Guanidine derivatives, their production and insecticides | Takeda Chemical Industries, Ltd. (JP) | 1995-08-02 | — | — | EP | disclosed |
| CN-1026981-C | Process for the preparation of guanidine derivatives | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-12-14 | — | — | CN | disclosed |
| CN-1077843-A | GUANIDINE DERIVATIVES, THEIR PRODUCTION AND INSECTICIDES | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-11-03 | — | — | CN | disclosed |
| EP-0493369-A1 | Guanidine derivatives, their production and insecticides | Takeda Chemical Industries, Ltd. (JP) | 1992-07-01 | — | — | EP | disclosed |
| US-5034404-A | Nitroguanidines as insecticides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| CN-1045261-A | Guanidine derivatives, their production and pesticides | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1990-09-12 | — | — | CN | disclosed |
| EP-0376279-A2 | Guanidine derivatives, their production and insecticides | Takeda Chemical Industries, Ltd. (JP) | 1990-07-04 | — | — | EP | disclosed |
| EP-0034481-B1 | 2-METHYL-5-THIAZOLE-METHYLAMINE AND CARBOXAMIDE DERIVATIVES | Grigg, Ronald Ernest (GB) | 1984-05-30 | — | — | EP | disclosed |
| EP-0034481-A1 | 2-Methyl-5-thiazole-methylamine and carboxamide derivatives | Grigg, Ronald Ernest (GB) | 1981-08-26 | — | — | EP | disclosed |
| US-4108994-A | 5-THIAZOLE-METHANE-AMINES, AND THEIR USE AS ANTILIPOLYTICS | ROUSSEL UCLAF (FR) | 1978-08-22 | — | — | US | disclosed |