Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 20/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24310544 | 0.87 | RIPK1 (0.41) | RIPK1 | |
| SCHEMBL24311033 | 0.79 | RIPK1 (0.38) | RIPK1 | |
| SCHEMBL25551290 | 0.76 | RIPK1 (0.47) | RIPK1 | |
| SCHEMBL25551288 | 0.76 | RIPK1 (0.47) | RIPK1 | |
| SCHEMBL24310388 | 0.76 | RIPK1 (0.41) | RIPK1 | |
| SCHEMBL24310736 | 0.76 | RIPK1 (0.41) | RIPK1 | |
| SCHEMBL24310373 | 0.74 | RIPK1 (0.37) | RIPK1 | |
| SCHEMBL20797888 | 0.69 | NR3C2 (0.44) | RIPK1 | |
| SCHEMBL20797887 | 0.69 | NR3C2 (0.44) | RIPK1 | |
| SCHEMBL24310625 | 0.67 | RIPK1 (0.39) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3978492-A1 | BICYCLIC COMPOUND AS RIP-1 KINASE INHIBITOR AND APPLICATION THEREOF | Medshine Discovery Inc. (CN) | 2022-04-06 | — | — | EP | disclosed |