Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2723490 | 0.88 | ALDH1A1 (0.57) | SMN1; SMN2HPGDTP53PKMNPSR1 | |
| SCHEMBL15053652 | 0.88 | DHODH (0.60) | SMN1; SMN2HPGDTP53PKMNPSR1 | |
| SCHEMBL20272240 | 0.80 | KDM4E (0.45) | SMN1; SMN2NPSR1ALDH1A1NPC1RAB9A | |
| SCHEMBL11388963 | 0.78 | SMN1; SMN2 (0.53) | SMN1; SMN2HPGDTP53PKMNPSR1 | |
| SCHEMBL11388960 | 0.78 | SMN1; SMN2 (0.53) | SMN1; SMN2HPGDTP53PKMNPSR1 | |
| SCHEMBL4466531 | 0.78 | SMN1; SMN2 (0.55) | SMN1; SMN2HPGDTP53PKMNPSR1 | |
| SCHEMBL18987970 | 0.77 | DHODH (0.60) | HPGDNPSR1ALDH1A1MEN1KMT2A | |
| SCHEMBL11388964 | 0.77 | SMN1; SMN2 (0.55) | SMN1; SMN2HPGDTP53PKMNPSR1 | |
| SCHEMBL7068073 | 0.74 | ALDH1A1 (0.55) | SMN1; SMN2HPGDTP53PKMNPSR1 | |
| SCHEMBL5295046 | 0.74 | DHODH (0.65) | HPGDPKMNPSR1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220073470-A1 | INHIBITORS OF CGAS ACTIVITY AS THERAPEUTIC AGENTS | BELLBROOK LABS, LLC | 2022-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220073470-A1 | INHIBITORS OF CGAS ACTIVITY AS THERAPEUTIC AGENTS | CGAS, STING1, IRF3 | SMN1; SMN2 2305/4885HPGD 1996/4885TP53 20/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.