Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 15/20 | 0.64 |
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | TTR | P02766 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | FBP1 | P09467 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24313 | 1.00 | P4HB (0.64) | P4HBMAOAMAOBTTRAPP | |
| SCHEMBL6983643 | 1.00 | P4HB (0.64) | P4HBMAOAMAOBTTRAPP | |
| SCHEMBL9779649 | 0.85 | P4HB (0.61) | P4HBMAOAMAOBFBP1 | |
| SCHEMBL9779652 | 0.85 | P4HB (0.61) | P4HBMAOAMAOBFBP1 | |
| SCHEMBL7363691 | 0.84 | P4HB (0.60) | P4HBMAOAMAOB | |
| SCHEMBL7363693 | 0.84 | P4HB (0.60) | P4HBMAOAMAOB | |
| SCHEMBL2136561 | 0.84 | P4HB (0.56) | P4HBMAOAMAOBFBP1 | |
| SCHEMBL16222087 | 0.84 | PDCD1 (0.61) | P4HBMAOAMAOBTTR | |
| SCHEMBL2136568 | 0.84 | P4HB (0.56) | P4HBMAOAMAOBFBP1 | |
| SCHEMBL6163160 | 0.84 | PDCD1 (0.61) | P4HBMAOAMAOBTTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594686-B | Millpulin A derivative, preparation method and medical application thereof | 沈阳药科大学 | 2023-10-13 | — | — | CN | claimed |
| CN-115594686-A | Millpuline A derivatives, and preparation method and medical application thereof | 沈阳药科大学（CN） | 2023-01-13 | — | — | CN | claimed |
| CN-115594686-B | Millpulin A derivative, preparation method and medical application thereof | 沈阳药科大学 | 2023-10-13 | — | — | CN | disclosed |
| CN-115594686-A | Millpuline A derivatives, and preparation method and medical application thereof | 沈阳药科大学（CN） | 2023-01-13 | — | — | CN | disclosed |
| CN-103168041-B | 3,4-pyrrolin is [1,2-A] pyrazine-2,8 (1H)-dicarboxamide derivatives, its preparation method and therepic use thereof also | SAI NUOFEI (FR) | 2015-08-26 | — | — | CN | disclosed |
| US-20150164889-A1 | CYCLOPROPYL AMIDE DERIVATIVES | ASTRAZENECA AB (SE) | 2015-06-18 | — | — | US | disclosed |
| US-20150164889-A1 | CYCLOPROPYL AMIDE DERIVATIVES | ASTRAZENECA AB (SE) | 2015-06-18 | — | — | US | disclosed |
| US-20150164888-A1 | CYCLOPROPYL AMIDE DERIVATIVES | ASTRAZENECA AB (SE) | 2015-06-18 | — | — | US | disclosed |
| US-20150164889-A1 | CYCLOPROPYL AMIDE DERIVATIVES | ASTRAZENECA AB (SE) | 2015-06-18 | — | — | US | disclosed |
| US-20150164888-A1 | CYCLOPROPYL AMIDE DERIVATIVES | ASTRAZENECA AB (SE) | 2015-06-18 | — | — | US | disclosed |
| US-20150164888-A1 | CYCLOPROPYL AMIDE DERIVATIVES | ASTRAZENECA AB (SE) | 2015-06-18 | — | — | US | disclosed |
| WO-2000047554-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS INC. (US) | 2000-08-17 | — | — | WO | disclosed |
| EP-1021410-A1 | PROSTAGLANDIN AGONISTS AND THEIR USE TO TREAT BONE DISORDERS | PFIZER INC. (US) | 2000-07-26 | — | — | EP | disclosed |
| US-6057342-A | INHIBITORS OF TRYPSIN-LIKE SERINE PROTEASE ENZYMES, ESPECIALLY FACTOR XA, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME AS ANTICOAGULANT AGENTS FOR TREATMENT AND PREVENTION OF THROMBOEMBOLIC DISORDERS | DUPONT PHARMACEUTICAL CO. (US) | 2000-05-02 | — | — | US | disclosed |
| EP-0934265-A1 | AMIDINOPHENYL-PYRROLIDINES, -PYRROLINES, AND -ISOXAZOLIDINES AND DERIVATIVES THEREOF | Du Pont Pharmaceuticals Company (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1999019300-A1 | PROSTAGLANDIN AGONISTS AND THEIR USE TO TREAT BONE DISORDERS | PFIZER INC. (US) | 1999-04-22 | — | — | WO | disclosed |
| WO-1998006694-A1 | AMIDINOPHENYL-PYRROLIDINES, -PYRROLINES, AND -ISOXAZOLIDINES AND DERIVATIVES THEREOF | DU PONT PHARMACEUTICALS COMPANY (US) | 1998-02-19 | — | — | WO | disclosed |
| US-5064959-A | Photoinitiators | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-11-12 | — | — | US | disclosed |
| EP-0153720-B1 | SPERGUALIN-RELATED COMPOUNDS HAVING A PHENYLENE GROUP, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 1988-11-09 | — | — | EP | disclosed |
| EP-0153720-A2 | Spergualin-related compounds having a phenylene group, a process for their preparation and their use as medicaments | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 1985-09-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150164888-A1 | CYCLOPROPYL AMIDE DERIVATIVES | HRH4, HRH2, HRH3 | P4HB 2927/4885MAOA 779/4885MAOB 1534/4885 |
| US-20150164889-A1 | CYCLOPROPYL AMIDE DERIVATIVES | HRH4, HRH2, HRH3 | P4HB 2927/4885MAOA 779/4885MAOB 1534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.