Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.42 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23217957 | 0.84 | KDM4E (0.40) | MAPTLMNA | |
| SCHEMBL24311930 | 0.81 | L3MBTL1 (0.43) | HTTL3MBTL1MAPTLMNASMN1; SMN2 | |
| SCHEMBL17536575 | 0.78 | L3MBTL1 (0.59) | HTTL3MBTL1MAPTLMNASMN1; SMN2 | |
| SCHEMBL25258837 | 0.78 | PDGFRB (0.60) | — | |
| SCHEMBL31052337 | 0.78 | PDGFRB (0.60) | — | |
| SCHEMBL22515674 | 0.76 | KMT2A (0.50) | MAPTLMNASMN1; SMN2AAK1 | |
| SCHEMBL30829553 | 0.74 | L3MBTL1 (0.62) | HTTL3MBTL1MAPTLMNASMN1; SMN2 | |
| SCHEMBL23217950 | 0.74 | CA12 (0.48) | HTTLMNAAAK1 | |
| SCHEMBL18254066 | 0.73 | HTT (0.81) | HTTL3MBTL1MAPTLMNASMN1; SMN2 | |
| SCHEMBL26462776 | 0.73 | TAAR1 (0.49) | HTTL3MBTL1MAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022076905-A1 | ALK5 INHIBITORS, CONJUGATES, AND USES THEREOF | SILVERBACK THERAPEUTICS, INC. (US) | 2022-04-14 | — | — | WO | disclosed |