Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 9/20 | 0.65 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.61 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.61 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.61 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.61 |
| ▸ | PLG | P00747 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.54 |
| ▸ | F2 | P00734 | 2/20 | 0.51 |
| ▸ | CASP3 | P42574 | 2/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP2 | P42575 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | IDE | P14735 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22769248 | 1.00 | FOLH1 (0.65) | FOLH1PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL16458328 | 0.97 | FOLH1 (0.62) | FOLH1PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL24312562 | 0.89 | FOLH1 (0.54) | FOLH1PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL24312559 | 0.88 | FOLH1 (0.60) | FOLH1PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL17244680 | 0.88 | FOLH1 (0.61) | FOLH1PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL22580893 | 0.87 | PRSS1 (0.53) | FOLH1PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL18133288 | 0.87 | TDP1 (0.69) | FOLH1PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL22769273 | 0.87 | FOLH1 (0.69) | FOLH1PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL10044328 | 0.86 | TDP1 (0.72) | FOLH1PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL16478827 | 0.86 | FOLH1 (0.64) | FOLH1PRSS1PRSS2PRSS3TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2670755-B1 | TRIFUNCTIONAL CROSSLINKING REAGENTS | ETH ZUERICH (CH) | 2016-10-12 | — | — | EP | disclosed |
| EP-2942351-B1 | TRIFUNCTIONAL CROSSLINKING REAGENTS | ETH ZUERICH (CH) | 2016-10-12 | — | — | EP | disclosed |
| EP-2942351-A1 | TRIFUNCTIONAL CROSSLINKING REAGENTS | ETH Zurich (CH) | 2015-11-11 | — | — | EP | disclosed |