⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24312610 | 0.86 | TDP1 (0.32) | — | |
| SCHEMBL24312536 | 0.85 | RIPK1 (0.31) | — | |
| SCHEMBL25013954 | 0.77 | — | — | |
| SCHEMBL25012471 | 0.77 | — | — | |
| SCHEMBL26214112 | 0.73 | — | — | |
| SCHEMBL26325704 | 0.72 | — | — | |
| SCHEMBL26317664 | 0.72 | RIPK1 (0.33) | — | |
| SCHEMBL26317120 | 0.72 | RIPK1 (0.31) | — | |
| SCHEMBL26316679 | 0.72 | RIPK1 (0.31) | — | |
| SCHEMBL25013997 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11814406-B2 | Compounds and methods for treatment of viral infections | GILEAD SCIENCES, INC. (US) | 2023-11-14 | — | — | US | disclosed |
| US-20230151043-A1 | COMPOUNDS AND METHODS FOR TREATMENT OF VIRAL INFECTIONS | GILEAD SCIENCES, INC. | 2023-05-18 | — | — | US | disclosed |
| US-20220081462-A1 | COMPOUNDS AND METHODS FOR TREATMENT OF VIRAL INFECTIONS | GILEAD SCIENCES, INC. | 2022-03-17 | — | — | US | disclosed |