Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.39 |
| ▸ | KDM1A | O60341 | 11/20 | 0.38 |
| ▸ | MAOB | P27338 | 5/20 | 0.38 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3237330 | 0.88 | EPHX1 (0.50) | KCNH2EPHX1GNAI3GNAO1GNAI1 | |
| SCHEMBL1955385 | 0.85 | EPHX1 (0.48) | KCNH2EPHX1GNAI3GNAO1GNAI1 | |
| SCHEMBL8721668 | 0.85 | — | — | |
| SCHEMBL5778312 | 0.83 | — | — | |
| SCHEMBL4709668 | 0.83 | — | — | |
| SCHEMBL4727038 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL29035917 | 0.82 | EPHX1 (0.46) | KCNH2EPHX1GNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL8942134 | 0.82 | ALDH1A1 (0.40) | KCNH2KDM1AALDH1A1HSD17B10MAOA | |
| Hydrochloric Acid SCHEMBL31208698 | 0.81 | KCNH2 (0.48) | KCNH2EPHX1GNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL29134411 | 0.81 | KCNH2 (0.48) | KCNH2EPHX1GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022074459-A2 | AUTOTAXIN INHIBITOR COMPOUNDS | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2022-04-14 | — | — | WO | disclosed |