Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24312363 | 0.99 | TDP1 (0.47) | TDP1HTTPOLBAPEX1TSHR | |
| SCHEMBL24312510 | 0.96 | HTT (0.44) | TDP1HTTPOLBAPEX1TSHR | |
| SCHEMBL24312528 | 0.91 | THRB (0.41) | TDP1HTTPOLBAPEX1TSHR | |
| SCHEMBL24312791 | 0.86 | MAPT (0.40) | TDP1HTTPOLBAPEX1TSHR | |
| SCHEMBL30394826 | 0.83 | SMYD2 (0.37) | HTTSMYD2CYP3A4SMN1; SMN2 | |
| SCHEMBL11521481 | 0.82 | TDP1 (0.48) | TDP1HTTPOLBAPEX1TSHR | |
| SCHEMBL30158998 | 0.81 | SMYD2 (0.36) | HTTSMYD2CYP3A4SMN1; SMN2 | |
| SCHEMBL31528916 | 0.80 | TBXA2R (0.43) | ALDH1A1 | |
| SCHEMBL19405748 | 0.80 | TBXA2R (0.43) | ALDH1A1 | |
| SCHEMBL17755998 | 0.80 | SMYD2 (0.42) | TDP1HTTSMYD2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022071286-A1 | LIQUID-CRYSTAL COMPOSITION, LIQUID-CRYSTAL DISPLAY ELEMENT PRODUCTION METHOD, AND LIQUID-CRYSTAL DISPLAY ELEMENT | 日産化学株式会社 | 2022-04-07 | — | — | WO | disclosed |