Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 8/20 | 0.43 |
| ▸ | HTR1A | P08908 | 7/20 | 0.43 |
| ▸ | HTR1D | P28221 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22769254 | 0.88 | KDM4E (0.44) | KDM4ETP53HTR1BHTR1AHTR1D | |
| SCHEMBL23895077 | 0.83 | KDM4E (0.40) | LMNAKDM4ETP53GAA | |
| SCHEMBL5949102 | 0.75 | PARP15 (0.46) | LMNAKDM4ETP53HTR1BHTR1A | |
| SCHEMBL12485019 | 0.75 | NR5A1 (0.58) | KDM4ETP53HTR1BHTR1AHTR1D | |
| SCHEMBL12483695 | 0.75 | NR5A1 (0.58) | KDM4ETP53HTR1BHTR1AHTR1D | |
| SCHEMBL9011532 | 0.73 | NR5A1 (0.55) | KDM4ETP53HTR1BHTR1AHTR1D | |
| SCHEMBL347395 | 0.71 | LTA4H (0.50) | KDM4ETP53HTR1BHTR1AHTR1D | |
| SCHEMBL12627591 | 0.70 | NR5A1 (0.53) | KDM4ETP53HTR1BHTR1AHTR1D | |
| SCHEMBL29285266 | 0.70 | LTA4H (0.56) | KDM4ETP53HTR1BHTR1AHTR1D | |
| SCHEMBL345720 | 0.70 | NR5A1 (0.56) | KDM4ETP53HTR1BHTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3981772-A1 | TETRA-FUNCTIONAL CHEMICAL PROBE AND METHOD FOR IDENTIFYING TARGET MEMBRANE PROTEIN FROM LIVING CELL OR LIVING TISSUE BY USING SAID PROBE | Otsuka Pharmaceutical Co., Ltd. (JP) | 2022-04-13 | — | — | EP | disclosed |