Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29302344 | 0.81 | ATM (0.40) | ATMCHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL23464957 | 0.81 | TSHR (0.42) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL5471213 | 0.79 | VHL (0.41) | ATMCHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL3827355 | 0.79 | VHL (0.41) | ATMCHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL8053252 | 0.79 | VHL (0.41) | ATMCHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL26079416 | 0.79 | ALDH1A1 (0.45) | LMNAMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL2492744 | 0.78 | VHL (0.40) | ATMCHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL12733445 | 0.78 | RECQL (0.52) | TSHRLMNASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL23371640 | 0.78 | ALDH1A1 (0.39) | ATMALBLMNACYP2C9HTR2A | |
| SCHEMBL13559785 | 0.76 | ALDH1A1 (0.48) | ATMMEN1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022074459-A2 | AUTOTAXIN INHIBITOR COMPOUNDS | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2022-04-14 | — | — | WO | disclosed |