Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | F10 | P00742 | 2/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8877926 | 0.80 | NAAA (0.66) | POLBNAAAL3MBTL1 | |
| SCHEMBL926090 | 0.76 | SMN1; SMN2 (0.42) | POLBSMN1; SMN2GAAHTTF10 | |
| SCHEMBL3213067 | 0.75 | SMN1; SMN2 (0.41) | POLBSMN1; SMN2GAAHTTKDM4E | |
| SCHEMBL9819875 | 0.75 | SMN1; SMN2 (0.44) | POLBSMN1; SMN2GAA | |
| SCHEMBL675612 | 0.75 | NAAA (0.64) | NAAA | |
| SCHEMBL13208084 | 0.74 | POLB (0.39) | POLBSMN1; SMN2GAAHTTF10 | |
| SCHEMBL24313412 | 0.74 | SMN1; SMN2 (0.38) | POLBSMN1; SMN2GAATSHRKDM4E | |
| SCHEMBL6959243 | 0.74 | — | — | |
| SCHEMBL15857711 | 0.73 | SMN1; SMN2 (0.36) | POLBSMN1; SMN2GAA | |
| SCHEMBL21641639 | 0.73 | SMN1; SMN2 (0.37) | POLBSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022074459-A2 | AUTOTAXIN INHIBITOR COMPOUNDS | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2022-04-14 | — | — | WO | disclosed |