Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.78 |
| ▸ | FKBP1A | P62942 | 10/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL428816 | 0.81 | L3MBTL1 (0.78) | L3MBTL1FKBP1APOLBTSHRALOX15 | |
| SCHEMBL12439630 | 0.81 | L3MBTL1 (0.78) | L3MBTL1FKBP1APOLBTSHRALDH1A1 | |
| SCHEMBL2262931 | 0.79 | L3MBTL1 (0.61) | L3MBTL1FKBP1APOLBTSHRALOX15 | |
| SCHEMBL9124397 | 0.78 | L3MBTL1 (0.72) | L3MBTL1FKBP1APOLBTSHRALOX15 | |
| SCHEMBL17490501 | 0.78 | L3MBTL1 (0.79) | L3MBTL1FKBP1APOLBTSHRALOX15 | |
| SCHEMBL16322843 | 0.77 | L3MBTL1 (0.70) | L3MBTL1FKBP1APOLBTSHRALOX15 | |
| SCHEMBL14654219 | 0.77 | L3MBTL1 (0.70) | L3MBTL1FKBP1APOLBTSHRALDH1A1 | |
| SCHEMBL18026620 | 0.77 | L3MBTL1 (0.70) | L3MBTL1FKBP1APOLBTSHRALDH1A1 | |
| SCHEMBL5986412 | 0.76 | L3MBTL1 (0.70) | L3MBTL1FKBP1APOLBTSHRALOX15 | |
| Iodoacetamide SCHEMBL21543897 | 0.76 | L3MBTL1 (0.53) | L3MBTL1FKBP1APOLBTSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3784666-B1 | ANTIPROLIFERATION COMPOUNDS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2022-03-16 | — | — | EP | disclosed |