Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | QDPR | P09417 | 3/20 | 0.33 |
| ▸ | ERN1 | O75460 | 3/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24439732 | 0.87 | ESR2 (0.31) | ESR2 | |
| SCHEMBL12174452 | 0.81 | HDAC4 (0.42) | ESR2QDPRERN1HDAC4HDAC2 | |
| SCHEMBL14302791 | 0.79 | — | — | |
| SCHEMBL24313735 | 0.78 | HTR2A (0.35) | ESR2QDPRCNR1 | |
| SCHEMBL29588792 | 0.78 | HTR2A (0.35) | ESR2QDPRCNR1 | |
| SCHEMBL20456768 | 0.75 | DAO (0.35) | — | |
| SCHEMBL24313909 | 0.75 | NPY5R (0.30) | — | |
| SCHEMBL22103530 | 0.75 | ERN1 (0.39) | QDPRERN1MAPT | |
| SCHEMBL24314202 | 0.75 | ESR2 (0.34) | ESR2QDPRERN1CYP3A4MAPT | |
| SCHEMBL29587536 | 0.75 | ESR2 (0.34) | ESR2QDPRERN1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081842-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |